相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Nucleotide biosynthesis arrest by silencing SHMT1 function via vitamin B6-coupled vector and effects on tumor growth inhibition
Shambhavi Pandey et al.
BIOMATERIALS (2014)
Action at a Distance: Allostery and the Development of Drugs to Target Cancer Cell Metabolism
Byron DeLaBarre et al.
CHEMISTRY & BIOLOGY (2014)
Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis
Itamar Kass et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Conformational transitions driven by pyridoxal-5′-phosphate uptake in the psychrophilic Serine hydroxymethyltransferase from Psychromonas ingrahamii
Sebastiana Angelaccio et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2014)
The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures
Francesco Angelucci et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2014)
Metabolic control of cell death
Douglas R. Green et al.
SCIENCE (2014)
Serine and glycine metabolism in cancer
Ivano Amelio et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
A. Paone et al.
CELL DEATH & DISEASE (2014)
Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia
Jiangbin Ye et al.
CANCER DISCOVERY (2014)
Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells
Christiaan F. Labuschagne et al.
CELL REPORTS (2014)
Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: The heme connection
Martino L. di Salvo et al.
MEDICAL HYPOTHESES (2013)
dbPTM 3.0: an informative resource for investigating substrate site specificity and functional association of protein post-translational modifications
Cheng-Tsung Lu et al.
NUCLEIC ACIDS RESEARCH (2013)
A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses
Hui Zheng et al.
CELL REPORTS (2013)
Structure-Based Mechanism for Early PLP-Mediated Steps of Rabbit Cytosolic Serine Hydroxymethyltransferase Reaction
Martino L. Di Salvo et al.
BIOMED RESEARCH INTERNATIONAL (2013)
Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis
Wen Cai Zhang et al.
CELL (2012)
Mitochondrial protein acetylation regulates metabolism
Kristin A. Anderson et al.
LYSINE-BASED POST-TRANSLATIONAL MODIFICATION OF PROTEINS (2012)
Crystal structures of the Chromobacterium violaceum?-transaminase reveal major structural rearrangements upon binding of coenzyme PLP
Maria S. Humble et al.
FEBS JOURNAL (2012)
Competition between Sumoylation and Ubiquitination of Serine Hydroxymethyltransferase 1 Determines Its Nuclear Localization and Its Accumulation in the Nucleus
Donald D. Anderson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Serine Hydroxymethyltransferase Anchors de Novo Thymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis
Donald D. Anderson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin
Uwe Mueller et al.
JOURNAL OF SYNCHROTRON RADIATION (2012)
Protein frustratometer: a tool to localize energetic frustration in protein molecules
Michael Jenik et al.
NUCLEIC ACIDS RESEARCH (2012)
Linking Crystallographic Model and Data Quality
P. Andrew Karplus et al.
SCIENCE (2012)
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Mohit Jain et al.
SCIENCE (2012)
REFMAC5 for the refinement of macromolecular crystal structures
Garib N. Murshudov et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
Serine hydroxymethyltransferase: A model enzyme for mechanistic, structural, and evolutionary studies
Rita Florio et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2011)
In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
Frederick Daidone et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
Richard Possemato et al.
NATURE (2011)
Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases
Giorgio Giardina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria
Donald D. Anderson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Trafficking of Intracellular Folates
Patrick J. Stover et al.
ADVANCES IN NUTRITION (2011)
Molecular replacement with MOLREP
Alexei Vagin et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
XDS
Wolfgang Kabsch
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Depleted folate pool and dysfunctional mitochondria associated with defective mitochondrial folate proteins sensitize Chinese ovary cell mutants to tert-butylhydroperoxide-induced oxidative stress and apoptosis
Yi-Ling Ye et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2010)
Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux
Qijun Wang et al.
SCIENCE (2010)
Role of a Conserved Active Site Cation-π Interaction in Escherichia coli Serine Hydroxymethyltransferase
Mirella Vivoli et al.
BIOCHEMISTRY (2009)
The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase
Rita Florio et al.
FEBS JOURNAL (2009)
SHMT1 and SHMT2 Are Functionally Redundant in Nuclear De novo Thymidylate Biosynthesis
Donald D. Anderson et al.
PLOS ONE (2009)
Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice
Amanda J. MacFarlane et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Inference of macromolecular assemblies from crystalline state
Evgeny Krissinel et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids
Ian W. Davis et al.
NUCLEIC ACIDS RESEARCH (2007)
The mechanism of addition of pyridoxal 5′-phosphate to Escherichia coli apo-serine hydroxymethyltransferase
Francesca Malerba et al.
BIOCHEMICAL JOURNAL (2007)
Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells
Cheryll Perry et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop
Gustavo Fenalti et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
GROMACS: Fast, flexible, and free
D Van der Spoel et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions
E Krissinel et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Pyridoxal phosphate inhibits dynamic subunit interchange among serine hydroxymethyltransferase tetramers
KA Zanetti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of amino acid residues, essential for maintaining the tetrameric structure of sheep liver cytosolic serine hydroxymethyltransferase, by targeted mutagenesis
VR Jala et al.
BIOCHEMICAL JOURNAL (2003)
Location of the pteroylpolyglutamate-binding site on rabbit cytosolic serine hydroxymethyltransferase
TF Fu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus -: Insights into the catalytic mechanism
V Trivedi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by 13C NMR
TF Fu et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2001)
Structure of a murine cytoplasmic serine hydroxymethyltransferase quinonoid ternary complex: Evidence for asymmetric obligate dimers
DME Szebenyi et al.
BIOCHEMISTRY (2000)
Crystal structure at 2.4 Å resolution of E-coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate
JN Scarsdale et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
分享论文
