相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
Zachary T. Schug et al.
CANCER CELL (2015)
Human Phosphoglycerate Dehydrogenase Produces the Oncometabolite D-2-Hydroxyglutarate
Jing Fan et al.
ACS CHEMICAL BIOLOGY (2015)
IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition
Andrew Kernytsky et al.
BLOOD (2015)
Histone deacetylase inhibitors: an overview of the clinical studies in solid tumors
Marije Slingerland et al.
ANTI-CANCER DRUGS (2014)
Development and classes of epigenetic drugs for cancer
Dashyant Dhanak et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Interpreting the language of histone and DNA modifications
Scott B. Rothbart et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2014)
Histone trimethylation at H3K4, H3K9 and H4K20 correlates with patient survival and tumor recurrence in early-stage colon cancer
Anne Benard et al.
BMC CANCER (2014)
Circulating Oncometabolite 2-Hydroxyglutarate Is a Potential Surrogate Biomarker in Patients with Isocitrate Dehydrogenase-Mutant Intrahepatic Cholangiocarcinoma
Darrell R. Borger et al.
CLINICAL CANCER RESEARCH (2014)
Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas
Luis Jaime Castro-Vega et al.
HUMAN MOLECULAR GENETICS (2014)
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
Atsushi Terunuma et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation
Fumiharu Ohka et al.
TUMOR BIOLOGY (2014)
A Systems Approach to Predict Oncometabolites via Context-Specific Genome-Scale Metabolic Networks
Hojung Nam et al.
PLOS COMPUTATIONAL BIOLOGY (2014)
SDH Mutations Establish a Hypermethylator Phenotype in Paraganglioma
Eric Letouze et al.
CANCER CELL (2013)
Histone 3 Lysine 9 Trimethylation Is Differentially Associated With Isocitrate Dehydrogenase Mutations in Oligodendrogliomas and High-Grade Astrocytomas
Sriram Venneti et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2013)
Metabolism of inflammation limited by AMPK and pseudo-starvation
Luke A. J. O'Neill et al.
NATURE (2013)
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1
Martje Toenjes et al.
NATURE MEDICINE (2013)
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas
P. Wang et al.
ONCOGENE (2013)
Concise Drug Review: Azacitidine and Decitabine
Ellen J. B. Derissen et al.
ONCOLOGIST (2013)
IDH1/IDH2 Mutations Define the Prognosis and Molecular Profiles of Patients with Gliomas: A Meta-Analysis
Peng Zou et al.
PLOS ONE (2013)
(R)-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
Julie-Aurore Losman et al.
SCIENCE (2013)
An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
Dan Rohle et al.
SCIENCE (2013)
Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation
Fang Wang et al.
SCIENCE (2013)
Serine, glycine and one-carbon units: cancer metabolism in full circle
Jason W. Locasale
NATURE REVIEWS CANCER (2013)
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
Patrick S. Ward et al.
CANCER CELL (2012)
Cancer epigenomics: beyond genomics
Juan Sandoval et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2012)
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors
Mengtao Xiao et al.
GENES & DEVELOPMENT (2012)
A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation
Christopher G. Duncan et al.
GENOME RESEARCH (2012)
IDH mutations in acute myeloid leukemia
Dinesh Rakheja et al.
HUMAN PATHOLOGY (2012)
IDH mutation impairs histone demethylation and results in a block to cell differentiation
Chao Lu et al.
NATURE (2012)
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
Peppi Koivunen et al.
NATURE (2012)
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
Sevin Turcan et al.
NATURE (2012)
R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1α upregulation in adult glioma
Susan C. Williams et al.
ACTA NEUROPATHOLOGICA (2011)
IDH1 R132H Decreases Proliferation of Glioma Cell Lines In Vitro and In Vivo
Linda B. C. Bralten et al.
ANNALS OF NEUROLOGY (2011)
Histone demethylases in chromatin cross-talks
Laure Verrier et al.
BIOLOGY OF THE CELL (2011)
Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
Wei Xu et al.
CANCER CELL (2011)
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
Rasheduzzaman Chowdhury et al.
EMBO REPORTS (2011)
IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours
M. Fernanda Amary et al.
JOURNAL OF PATHOLOGY (2011)
Charting histone modifications and the functional organization of mammalian genomes
Vicky W. Zhou et al.
NATURE REVIEWS GENETICS (2011)
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
Zachary J. Reitman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Dimitrios Anastasiou et al.
SCIENCE (2011)
Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
Houtan Noushmehr et al.
CANCER CELL (2010)
Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
Maria E. Figueroa et al.
CANCER CELL (2010)
SDHA is a tumor suppressor gene causing paraganglioma
Nelly Burnichon et al.
HUMAN MOLECULAR GENETICS (2010)
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
Amar J. Majmundar et al.
MOLECULAR CELL (2010)
Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl-CoA/acetate metabolism
Yukie Yoshii et al.
CANCER SCIENCE (2009)
18F-FDG PET and PET/CT in the Evaluation of Cancer Treatment Response
Simona Ben-Haim et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Lenny Dang et al.
NATURE (2009)
Linking DNA methylation and histone modification: patterns and paradigms
Howard Cedar et al.
NATURE REVIEWS GENETICS (2009)
IDH1 and IDH2 Mutations in Gliomas
Hai Yan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α
Shimin Zhao et al.
SCIENCE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
Kathryn E. Wellen et al.
SCIENCE (2009)
Expanding chemical biology of 2-oxoglutarate oxygenases
Christoph Loenarz et al.
NATURE CHEMICAL BIOLOGY (2008)
An integrated genomic analysis of human glioblastoma Multiforme
D. Williams Parsons et al.
SCIENCE (2008)
Global histone modifications predict prognosis of resected non-small-cell lung cancer
Fabrice Barlesi et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
A high glycolytic flux supports the proliferative potential of murine embryonic stem cells
Hiroshi Kondoh et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
JS Isaacs et al.
CANCER CELL (2005)
Global histone modification patterns predict risk of prostate cancer recurrence
DB Seligson et al.
NATURE (2005)
Clinical features of multiple cutaneous and uterine leiomyomatosis - An underdiagnosed tumor syndrome
NA Alam et al.
ARCHIVES OF DERMATOLOGY (2005)
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
MA Selak et al.
CANCER CELL (2005)
Lactate and oxygen constitute a fundamental regulatory mechanism in wound healing
O Trabold et al.
WOUND REPAIR AND REGENERATION (2003)
[Fluorine-18]Fluorodeoxyglucose positron emission tomography, DNA ploidy and growth fraction in squamous-cell carcinomas of the head and neck
R Jacob et al.
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES (2001)
Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma
D Astuti et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
Mutations in SDHC cause autosomal dominant paraganglioma, type 3
S Niemann et al.
NATURE GENETICS (2000)
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
BE Baysal et al.
SCIENCE (2000)