4.4 Article

Tetraspanin blockage reduces exosome-mediated HIV-1 entry

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ARCHIVES OF VIROLOGY
卷 163, 期 6, 页码 1683-1689

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SPRINGER WIEN
DOI: 10.1007/s00705-018-3737-6

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资金

  1. American Association of Immunologists Careers in Immunology Fellowship Program
  2. Gorgas Memorial Foundation Research Grant Award
  3. National Institutes of Health [5R01AI089337-04]
  4. UAB-CCTS grant [UL1TR001417]
  5. UAB CFAR
  6. NIH [NIH]
  7. UAB CFAR Virology Core, which is part of the UAB CFAR [P30-AI-27767]
  8. Office of the Vice President of Research
  9. Cancer Center Support Grant [P30 CA013148]
  10. Rheumatic Disease Core Center [P30 AR048311]

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HIV-1 is one of the most studied retroviruses. The role of exosomes in HIV-1 entry and pathogenesis are beginning to be appreciated. Exosomes can incorporate host proteins that are also contained in viruses (e.g., tetraspanins).

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