期刊
APPLIED PHYSICS LETTERS
卷 112, 期 3, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.5005525
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资金
- NIH [R01 NX087494, R01 GM114188]
- NSF [CBET-1404080, DBI 1256178]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM114188] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS087494] Funding Source: NIH RePORTER
A plasmonic micropillar platform with self-organized gold nanospheres is reported for the precision cell traction force measurement across a large field-of-view (FOV). Gold nanospheres were implanted into the tips of polymer micropillars by annealing gold microdisks with nanosecond laser pulses. Each gold nanosphere is physically anchored in the center of a pillar tip and serves as a strong, point-source-like light scattering center for each micropillar. This allows a micropillar to be clearly observed and precisely tracked even under a low magnification objective lens for the concurrent and precision measurement across a large FOV. A spatial resolution of 30 nm for the pillar deflection measurement has been accomplished on this platform with a 20 x objective lens. Published by AIP Publishing.
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