期刊
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
卷 124, 期 5, 页码 -出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00339-018-1804-1
关键词
-
资金
- Board of Research in Nuclear Sciences (BRNS), Department of Atomic Energy (DAE), Government of India [34/14/10/2017-BRNS/34285]
In this paper, graphene-coated black phosphorus at the metal surface for the detection of DNA hybridization event is numerically demonstrated. The strategy consists of placing the sensing medium on top of black phosphorus-graphene-coated SPR which interfaces with phosphate-buffered saline solution carrying single-stranded DNA. Upon hybridization with its complementary DNA, desorption of the nanostructures takes place and thus enables the sensitive detection of the DNA hybridization event. The proposed sensor exhibits a sensitivity (125 (omicron)/RIU), detection accuracy (0.95) and quality factor (13.62 RIU-1) for complementary DNA. In comparison with other reported papers, our suggested sensor provides much better performance. Thus, this label-free DNA detection platform should spur off new interest towards the use of black phosphorus-graphene-coated SPR interfaces.
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