期刊
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
卷 102, 期 8, 页码 3583-3594出版社
SPRINGER
DOI: 10.1007/s00253-018-8890-z
关键词
Escherichia coli; Corynebacterium glutamicum; Diamine; Omega-amino acid; Lactam; Metabolic engineering
Common plastics such as polyamides are derived typically from petroleum or natural gas. Fossil-based polyamide production often involves toxic precursors or intermediates. By contrast, bio-based polyamides offer a realistic alternative. Bio-based routes to monomeric precursors of polyamides such as diamines, dicarboxylic acids, and omega-amino acids have been developed. Recent advances in the metabolic engineering of the biotechnologically relevant Escherichia coli and Corynebacterium glutamicum for the production of monoalkylamines such as omega-amino acids as well as diamines are presented.
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