期刊
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
卷 102, 期 17, 页码 7319-7331出版社
SPRINGER
DOI: 10.1007/s00253-018-9187-y
关键词
Long noncoding RNA; lncRNA; Yeast; Saccharomyces cerevisiae; Schizosaccharomyces pombe; Trichoderma reesei
资金
- Austrian Science Fund (FWF)
- Austrian Science Fund (FWF) [P26618]
- Novozymes
- Austrian Federal Ministry of Science, Research and Economy
- National Foundation for Research, Technology and Development
- Austrian Science Fund (FWF) [P26618] Funding Source: Austrian Science Fund (FWF)
Long noncoding RNAs (lncRNAs) are crucial players in epigenetic regulation. They were initially discovered in human, yet they emerged as common factors involved in a number of central cellular processes in several eukaryotes. For example, in the past decade, research on lncRNAs in yeast has steadily increased. Several examples of lncRNAs were described in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Also, screenings for lncRNAs in ascomycetes were performed and, just recently, the first full characterization of a lncRNA was performed in the filamentous fungus Trichoderma reesei. In this review, we provide a broad overview about currently known fugal lncRNAs. We make an attempt to categorize them according to their functional context, regulatory strategies or special properties. Moreover, the potential of lncRNAs as a biotechnological tool is discussed.
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