期刊
EMERGING INFECTIOUS DISEASES
卷 22, 期 6, 页码 1052-1056出版社
CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2206.151080
关键词
-
资金
- Endeavour Postgraduate Scholarship [3781_2014]
- Australia National University Higher Degree Scholarship
- Fondo para la Innovacion, Ciencia, y Tecnologia Scholarship [095-FINCyT-BDE-2014]
- National Health and Medical Research Council, Australia [1002608]
Influenza infection manifests in a wide spectrum of severity, including symptomless pathogen carriers. We conducted a systematic review and meta-analysis of 55 studies to elucidate the proportional representation of these asymptomatic infected persons. We observed extensive heterogeneity among these studies. The prevalence of asymptomatic carriage (total absence of symptoms) ranged from 5.2% to 35.5% and subclinical cases (illness that did not meet the criteria for acute respiratory or influenza-like illness) from 25.4% to 61.8%. Statistical analysis showed that the heterogeneity could not be explained by the type of influenza, the laboratory tests used to detect the virus, the year of the study, or the location of the study. Projections of infection spread and strategies for disease control require that we identify the proportional representation of these insidious spreaders early on in the emergence of new influenza subtypes or strains and track how this rate evolves over time and space.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据