期刊
BIOFABRICATION
卷 8, 期 2, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/1758-5090/8/2/022001
关键词
3D printing; microfluidics; low-cost fabrication; additive manufacturing; lab-on-a-chip
资金
- American Heart Association Scientist Development Grant [15SDG25080056]
- University of Connecticut Research Excellence Program award
- University of Connecticut Provost's Teaching Innovation Mini Grant award
Microfluidics is a flourishing field, enabling a wide range of biochemical and clinical applications such as cancer screening, micro-physiological system engineering, high-throughput drug testing, and point-of-care diagnostics. However, fabrication of microfluidic devices is often complicated, time consuming, and requires expensive equipment and sophisticated clean room facilities. Three-dimensional (3D) printing presents a promising alternative to traditional techniques such as lithography and PDMS-glass bonding, not only by enabling rapid design iterations in the development stage, but also by reducing the costs associated with institutional infrastructure, equipment installation, maintenance, and physical space. With the recent advancements in 3D printing technologies, highly complex microfluidic devices can be fabricated via single-step, rapid, and cost-effective protocols, making microfluidics more accessible to users. In this review, we discuss a broad range of approaches for the application of 3D printing technology to fabrication of micro-scale lab-on-a-chip devices.
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