期刊
ANNUAL REVIEW OF PHYTOPATHOLOGY, VOL 56
卷 56, 期 -, 页码 479-512出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-phyto-080417-050158
关键词
genome editing; disease resistance; sequence-specific nucleases; TALENs; CRISPR-Cas9; susceptibility genes
资金
- BBSRC [BBS/E/J/000CA523, BBS/E/J/000PR9797, BB/M022315/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BBS/E/J/000CA523] Funding Source: Medline
Genome editing by sequence-specific nucleases (SSNs) has revolutionized biology by enabling targeted modifications of genomes. Although routine plant genome editing emerged only a few years ago, we are already witnessing the first applications to improve disease resistance. In particular, CRISPR-Cas9 has democratized the use of genome editing in plants thanks to the ease and robustness of this method. Here, we review the recent developments in plant genome editing and its application to enhancing disease resistance against plant pathogens. In the future, bioedited disease resistant crops will become a standard tool in plant breeding.
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