期刊
EXPERT REVIEW OF PROTEOMICS
卷 12, 期 4, 页码 329-331出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/14789450.2015.1064771
关键词
antibody bead arrays; biomarkers; biomarkers validation; proteomics; SomaScan; targeted mass spectrometry
Noninvasive molecular biomarkers are becoming attractive tools to monitor disease progression, aid drug development programs and use as surrogate outcome measures in clinical trials. Cutting edge proteomic methods to assay biomarkers in body fluids have been developed in the past few years, but transitioning them to clinical practice has been slow and depends on the qualification of both the method and the biomarker.
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