期刊
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
卷 15, 期 5, 页码 607-615出版社
TAYLOR & FRANCIS AS
DOI: 10.1586/14737159.2015.1027195
关键词
control; diagnosis; DNA; elimination; human African trypanosomiasis; RNA; sleeping sickness; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense
类别
A variety of molecular diagnostic tests for human African trypanosomiasis (HAT) (sleeping sickness) has been developed. Some are effectively used for research and confirmation diagnosis in travel medicine, usually following non-standardized protocols. Others have become commercially available as diagnostic kits. WHO aims to eliminate HAT as a public health problem by the year 2020, and zero transmission by the year 2030. This article gives an overview of the recent progress in molecular diagnostics for sleeping sickness, including the most recent data on test performances. Also discussed is how molecular diagnostics can play an important role in the process toward the elimination of HAT.
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