期刊
EXPERT OPINION ON THERAPEUTIC TARGETS
卷 19, 期 8, 页码 1127-1138出版社
TAYLOR & FRANCIS LTD
DOI: 10.1517/14728222.2015.1028361
关键词
dysbiosis; dyslipidemia; gut microbiota; inflammation; insulin resistance; obesity
Introduction: Probiotics are defined as live microorganisms that when administered in adequate amounts confer health benefits to the host. The consumption of probiotics has gained increasing recognition from the scientific community due to the promising effects on metabolic health through gut microbiota modulation. Areas covered: This article presents a review of scientific studies investigating probiotic species and their effects on different risk factors of the metabolic syndrome (MetS). This article also presents a summary of the major mechanisms involved with gut microbiota and the components of the MetS and raises the key issues to be considered by scientists in search of probiotics species for treatment of patients suffering from this metabolic disorder. Expert opinion: Probiotics may confer numerous health benefits to the host through positive gut microbiota modulation. The strain selection is the most important factor for determining health effects. Further studies may consider gut microbiota as a novel target for prevention and management of MetS components and other cardiovascular risks.
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