相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The Role of Endoplasmic Reticulum Stress in Human Pathology
Scott A. Oakes et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10 (2015)
Sensitization to docetaxel in prostate cancer cells by green tea and quercetin
Piwen Wang et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2015)
Epigallocatechin gallate, ellagic acid, and rosmarinic acid perturb dNTP pools and inhibit de novo DNA synthesis and proliferation of human HL-60 promyelocytic leukemia cells: Synergism with arabinofuranosylcytosine
Philipp Saiko et al.
PHYTOMEDICINE (2015)
Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit
Indrajit Das et al.
SCIENCE (2015)
Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity
M. Halliday et al.
CELL DEATH & DISEASE (2015)
Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress
Yong-Jie Zhang et al.
ACTA NEUROPATHOLOGICA (2014)
Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi
Lai-Ling Du et al.
AGE (2014)
Low-Power Inversion Recovery MRI Preserves Brain Tissue Contrast for Patients with Parkinson Disease with Deep Brain Stimulators
S. N. Sarkar et al.
AMERICAN JOURNAL OF NEURORADIOLOGY (2014)
Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 1. An overview
Estefanie Dufey et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)
Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 3. Orchestrating the unfolded protein response in oncogenesis: an update
Serge N. Manie et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)
MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis
Xiaojie Zhang et al.
AUTOPHAGY (2014)
Enhanced inhibition of prostate cancer xenograft tumor growth by combining quercetin and green tea
Piwen Wang et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2014)
Extra virgin olive oil intake delays the development of amyotrophic lateral sclerosis associated with reduced reticulum stress and autophagy in muscle of SOD1G93A mice
Sara Olivan et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2014)
Protein Disulfide Isomerase A6 Controls the Decay of IRE1α Signaling via Disulfide-Dependent Association
Davide Eletto et al.
MOLECULAR CELL (2014)
Druggable sensors of the unfolded protein response
Dustin J. Maly et al.
NATURE CHEMICAL BIOLOGY (2014)
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
Claudio Hetz et al.
NATURE REVIEWS NEUROSCIENCE (2014)
Resveratrol Enhances Palmitate-Induced ER Stress and Apoptosis in Cancer Cells
Cristina Rojas et al.
PLOS ONE (2014)
Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
Pamela Valdes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Addicted to secrete - novel concepts and targets in cancer therapy
Nicolas Dejeans et al.
TRENDS IN MOLECULAR MEDICINE (2014)
Targeting autophagy in neurodegenerative diseases
Rene L. Vidal et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors
Mario Sanches et al.
NATURE COMMUNICATIONS (2014)
Olive-Oil-Derived Oleocanthal Enhances β-Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer's Disease: In Vitro and in Vivo Studies
Alaa H. Abuznait et al.
ACS CHEMICAL NEUROSCIENCE (2013)
When ER stress reaches a dead end
Hery Urra et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Targeting endoplasmic reticulum stress in metabolic disease
Stewart Siyan Cao et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2013)
Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention
Pavel Tsaytler et al.
FEBS JOURNAL (2013)
Identification of a Novel Endoplasmic Reticulum Stress Response Element Regulated by XBP1
Michael Misiewicz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits
Tao Ma et al.
NATURE NEUROSCIENCE (2013)
Targeting the unfolded protein response in disease
Claudio Hetz et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis
Soledad Matus et al.
PLOS ONE (2013)
The Polyphenol Oleuropein Aglycone Protects TgCRND8 Mice against A beta Plaque Pathology
Cristina Grossi et al.
PLOS ONE (2013)
Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
Julie A. Moreno et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
The unfolded protein response in Alzheimer's disease
Victor Hugo Cornejo et al.
SEMINARS IN IMMUNOPATHOLOGY (2013)
Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development
Jeffrey M. Axten et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Pharmacological brake-release of mRNA translation enhances cognitive memory
Carmela Sidrauski et al.
ELIFE (2013)
Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma
Naoya Mimura et al.
BLOOD (2012)
Antioxidant properties of natural polyphenols and their therapeutic potentials for Alzheimer's disease
Dong-Young Choi et al.
BRAIN RESEARCH BULLETIN (2012)
Protein disulfide isomerases in neurodegeneration: From disease mechanisms to biomedical applications
Catherine I. Andreu et al.
FEBS LETTERS (2012)
Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)
Jeffrey M. Axten et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Development of a Grp94 inhibitor
Adam S. Duerfeldt et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Claudio Hetz
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson's Disease
Koji Hashida et al.
PLOS ONE (2012)
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
Benedict C. S. Cross et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment
Shili Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
InterfERing with endoplasmic reticulum stress
Honorata Kraskiewicz et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Activation of the unfolded protein response enhances motor recovery after spinal cord injury
V. Valenzuela et al.
CELL DEATH & DISEASE (2012)
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
Ioanna Papandreou et al.
BLOOD (2011)
Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives
D. Chen et al.
CURRENT CANCER DRUG TARGETS (2011)
Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum
Fabio Martinon et al.
CURRENT OPINION IN IMMUNOLOGY (2011)
Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells
Feng-Ming Wang et al.
EXPERIMENTAL HEMATOLOGY (2011)
Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds
Mario Caruana et al.
FEBS LETTERS (2011)
Potent and Selective Inhibitors of the Inositol-requiring Enzyme 1 Endoribonuclease
Kori Volkmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Unfolded protein response in cancer: the Physician's perspective
Xuemei Li et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2011)
Fighting neurodegeneration with rapamycin: mechanistic insights
Jordi Bove et al.
NATURE REVIEWS NEUROSCIENCE (2011)
The Potential of Protein Disulfide Isomerase as a Therapeutic Drug Target
Maola M. G. Khan et al.
ONCOLOGY RESEARCH (2011)
Dual and opposing roles of the unfolded protein response regulated by IRE1α and XBP1 in proinsulin processing and insulin secretion
Ann-Hwee Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
Peter Walter et al.
SCIENCE (2011)
Complementary Cell-Based High-Throughput Screens Identify Novel Modulators of the Unfolded Protein Response
Andrew M. Fribley et al.
JOURNAL OF BIOMOLECULAR SCREENING (2011)
Berberine reduces endoplasmic reticulum stress and improves insulin signal transduction in Hep G2 cells
Zeng-si Wang et al.
ACTA PHARMACOLOGICA SINICA (2010)
Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction (Publication with Expression of Concern. See vol. 53, pg. 709, 2021)
Ji Hyun Choi et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2010)
Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract
Gregory J. Brewer et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2010)
Sodium 4-phenylbutyrate protects against spinal cord ischemia by inhibition of endoplasmic reticulum stress
Taketomo Mizukami et al.
JOURNAL OF VASCULAR SURGERY (2010)
Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1
R. Luke Wiseman et al.
MOLECULAR CELL (2010)
Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins
Benjamin G. Hoffstrom et al.
NATURE CHEMICAL BIOLOGY (2010)
Alpha-tocopherol quinone inhibits beta-amyloid aggregation and cytotoxicity, disaggregates preformed fibrils and decreases the production of reactive oxygen species, NO and inflammatory cytokines
Shi-gao Yang et al.
NEUROCHEMISTRY INTERNATIONAL (2010)
Post-treatment of a BiP inducer prevents cell death after middle cerebral artery occlusion in mice
Yasuhisa Oida et al.
NEUROSCIENCE LETTERS (2010)
Inhibitory effect of ethanol extract of Magnolia officinalis and 4-O-methylhonokiol on memory impairment and neuronal toxicity induced by beta-amyloid
Jae Woong Lee et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2010)
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
Jan Bieschke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance
Lale Ozcan et al.
CELL METABOLISM (2009)
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
Claudio Hetz et al.
GENES & DEVELOPMENT (2009)
Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome
Claudio Hetz et al.
MOLECULAR CELL (2009)
Design, Synthesis, and Biological Evaluation of Conformationally Constrained cis-Amide Hsp90 Inhibitors
Adam S. Duerfeldt et al.
ORGANIC LETTERS (2009)
Characterization of α-synuclein interactions with selected aggregation-inhibiting small molecules
Jampani Nageswara Rao et al.
BIOCHEMISTRY (2008)
Flavonols and flavones as BACE-1 inhibitors: Structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features
Yoshiari Shimmyo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2008)
Protein quality control in the early secretory pathway
Tiziana Anelli et al.
EMBO JOURNAL (2008)
Kaempferol protects ischemia/reperfusion-induced cardiac damage through the regulation of endoplasmic reticulum stress
Do-Sung Kim et al.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2008)
Grape-derived polyphenolics prevent Aβ oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease
Jun Wang et al.
JOURNAL OF NEUROSCIENCE (2008)
GTPase-mediated regulation of the unfolded protein response in Caenorhabditis elegans is dependent on the AAA+ ATPase CDC-48
Marie-Elaine Caruso et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
Dagmar E. Ehrnhoefer et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Involvement of endoplasmic reticulum stress in the neuronal death induced by transient forebrain ischemia in gerbil
Y. Oida et al.
NEUROSCIENCE (2008)
A molecular chaperone inducer protects neurons from ER stress
T. Kudo et al.
CELL DEATH AND DIFFERENTIATION (2008)
Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation
Yoshinori Tsukumo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6α and XBP1
Keisuke Yamamoto et al.
DEVELOPMENTAL CELL (2007)
Hsp90: A novel target for the disruption of multiple signaling cascades
Stephanie C. Bishop et al.
CURRENT CANCER DRUG TARGETS (2007)
ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
Y. Kouroku et al.
CELL DEATH AND DIFFERENTIATION (2007)
Inhibition of proteasome activity by the dietary flavonoid apigenin is associated with growth inhibition in cultured breast cancer cells and xenografts
Di Chen et al.
BREAST CANCER RESEARCH (2007)
Structure-proteasome-inhibitory activity relationships of dietary flavonoids in human cancer cells
Di Chen et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2007)
Phase I dose escalation clinical trial of phenylbutyrate sodium administered twice daily to patients with advanced solid tumors
Luis H. Camacho et al.
INVESTIGATIONAL NEW DRUGS (2007)
Autophagy is activated for cell survival after endoplasmic reticulum stress
Maiko Ogata et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP
Adrienne W. Paton et al.
NATURE (2006)
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
Umut Oezcan et al.
SCIENCE (2006)
Inhibitors of α-synuclein oligomerization and toxicity:: a future therapeutic strategy for Parkinson's disease and related disorders
Dena A. M. Amer et al.
EXPERIMENTAL BRAIN RESEARCH (2006)
The affinity of a major Ca2+ binding site on GRP78 is differentially enhanced by ADP and ATP
HK Lamb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells
D Chen et al.
BIOCHEMICAL PHARMACOLOGY (2005)
A selective inhibitor-of eIF2α dephosphorylation protects cells from ER stress
M Boyce et al.
SCIENCE (2005)
Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway
NR Jana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease
M Tanaka et al.
NATURE MEDICINE (2004)
The flavonoid baicalein inhibits fibrillation of α-synuclein and disaggregates existing fibrils
M Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A transgenic mouse model for monitoring endoplasmic reticulum stress
T Iwawaki et al.
NATURE MEDICINE (2004)
Sodium 4-phenylbutyrate protects against cerebral ischemic injury
X Qi et al.
MOLECULAR PHARMACOLOGY (2004)
Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein
A Kazi et al.
BIOCHEMICAL PHARMACOLOGY (2003)
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells
AH Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
AH Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Development of Radicicol Analogues
Shiro Soga et al.
CURRENT CANCER DRUG TARGETS (2003)
Unfolding the role of protein misfolding in neurodegenerative diseases
C Soto
NATURE REVIEWS NEUROSCIENCE (2003)
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic model of Huntington's disease
CD Keene et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
IREI-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
K Lee et al.
GENES & DEVELOPMENT (2002)
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
M Calfon et al.
NATURE (2002)
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
H Yoshida et al.
CELL (2001)
Perk is essential for translational regulation and cell survival during the unfolded protein response
HP Harding et al.
MOLECULAR CELL (2000)
分享论文
