相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Cancer Statistics, 2014
Rebecca Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2014)
The Use of Metformin in Patients with Prostate Cancer and the Risk of Death
Leah Bensimon et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2014)
Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling
John W. Scott et al.
CHEMISTRY & BIOLOGY (2014)
A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis (vol 6, pg 519, 2014)
Giorgia Zadra et al.
EMBO MOLECULAR MEDICINE (2014)
Association Between Metformin Use and Mortality in Patients With Prostate Cancer: Explained by Confounding by Indication?
Marjolein M. J. Zanders et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent
Xiaona Liu et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch
J. B. Tennakoon et al.
ONCOGENE (2014)
Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model
H. G. Nguyen et al.
ONCOGENE (2014)
A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation
Jennifer Munkley et al.
ONCOTARGET (2014)
Transcriptomic analysis reveals inhibition of androgen receptor activity by AMPK in prostate cancer cells
Sarah Jurmeister et al.
ONCOTARGET (2014)
Regulation of the pentose phosphate pathway by an androgen receptor-mTOR-mediated mechanism and its role in prostate cancer cell growth
E. Tsouko et al.
ONCOGENESIS (2014)
Metformin directly acts on mitochondria to alter cellular bioenergetics
Sylvia Andrzejewski et al.
CANCER & METABOLISM (2014)
Phytochemicals from Cruciferous Vegetables, Epigenetics, and Prostate Cancer Prevention
Gregory W. Watson et al.
AAPS JOURNAL (2013)
The Androgen Receptor Induces a Distinct Transcriptional Program in Castration-Resistant Prostate Cancer in Man
Naomi L. Sharma et al.
CANCER CELL (2013)
Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism
Sarah-Maria Fendt et al.
CANCER RESEARCH (2013)
AMPK Activation by Oncogenesis Is Required to Maintain Cancer Cell Proliferation in Astrocytic Tumors
Marcos Rios et al.
CANCER RESEARCH (2013)
Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy
Joungmok Kim et al.
CELL (2013)
The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation
Gabriel Leprivier et al.
CELL (2013)
AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer
D. Grahame Hardie
DIABETES (2013)
Metformin and the Incidence of Cancer in Patients With Diabetes: A Nested Case-Control Study
Shu-Yi Wang et al.
DIABETES CARE (2013)
Use of aspirin, but not other non-steroidal anti-inflammatory drugs is associated with decreased prostate cancer risk at the population level
Thea Veitonmaki et al.
EUROPEAN JOURNAL OF CANCER (2013)
Metformin and Prostate Cancer: Reduced Development of Castration-resistant Disease and Prostate Cancer Mortality
Daniel E. Spratt et al.
EUROPEAN UROLOGY (2013)
Agonists of luteinizing hormone-releasing hormone in prostate cancer
Ferenc G. Rick et al.
EXPERT OPINION ON PHARMACOTHERAPY (2013)
The Time Is Ripe for a Randomized Trial of Metformin in Clinically Localized Prostate Cancer
Kathryn L. Penney et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
Metformin Use and All-Cause and Prostate Cancer-Specific Mortality Among Men With Diabetes
David Margel et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
Association Between Metformin Use and Risk of Prostate Cancer and Its Grade
David Margel et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)
Genomic deletion of MAP3K7 at 6q12-22 is associated with early PSA recurrence in prostate cancer and absence of TMPRSS2:ERG
Martina Kluth et al.
MODERN PATHOLOGY (2013)
Zinc transporters in prostate cancer
M-C Franz et al.
MOLECULAR ASPECTS OF MEDICINE (2013)
Phosphorylation of BRAF by AMPK Impairs BRAF-KSR1 Association and Cell Proliferation
Che-Hung Shen et al.
MOLECULAR CELL (2013)
AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1
Ning Wu et al.
MOLECULAR CELL (2013)
Androgens Promote Prostate Cancer Cell Growth through Induction of Autophagy
Yan Shi et al.
MOLECULAR ENDOCRINOLOGY (2013)
Resveratrol worsens survival in SCID mice with prostate cancer xenografts in a cell-line specific manner, through paradoxical effects on oncogenic pathways
Joseph C. Klink et al.
PROSTATE (2013)
Metformin does not affect risk of biochemical recurrence following radical prostatectomy: results from the SEARCH database
E. H. Allott et al.
PROSTATE CANCER AND PROSTATIC DISEASES (2013)
Inhibition of Calcium/Calmodulin-Dependent Protein Kinase Kinase β and Calcium/Calmodulin-Dependent Protein Kinase IV Is Detrimental in Cerebral Ischemia
Louise D. McCullough et al.
STROKE (2013)
An update on the use of degarelix in the treatment of advanced hormone-dependent prostate cancer
Ferenc G. Rick et al.
ONCOTARGETS AND THERAPY (2013)
Cancer Metabolism: New Validated Targets for Drug Discovery
Federica Sotgia et al.
ONCOTARGET (2013)
The changing landscape in the treatment of metastatic castration-resistant prostate cancer
Joelle El-Amm et al.
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2013)
The influence of antidiabetic medications on the development and progression of prostate cancer
Anna Hitron et al.
CANCER EPIDEMIOLOGY (2012)
Suppression of Tak1 Promotes Prostate Tumorigenesis
Min Wu et al.
CANCER RESEARCH (2012)
SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
Nathan L. Price et al.
CELL METABOLISM (2012)
Regulation of LKB1 expression by sex hormones in adipocytes
K. J. McInnes et al.
INTERNATIONAL JOURNAL OF OBESITY (2012)
A Regulatory Feedback Loop Between Ca2+/Calmodulin-dependent Protein Kinase Kinase 2 (CaMKK2) and the Androgen Receptor in Prostate Cancer Progression
Loukia G. Karacosta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
Sebastian Alers et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
AMPK Regulates Mitotic Spindle Orientation through Phosphorylation of Myosin Regulatory Light Chain
Jose T. Thaiparambil et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
Sang-Min Jeon et al.
NATURE (2012)
AMPK: a nutrient and energy sensor that maintains energy homeostasis
D. Grahame Hardie et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Activation of AMP-Activated Protein Kinase by 3,3′-Diindolylmethane (DIM) Is Associated with Human Prostate Cancer Cell Death In Vitro and In Vivo
Di Chen et al.
PLOS ONE (2012)
The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase
Simon A. Hawley et al.
SCIENCE (2012)
Control of Glycolytic Flux by AMP-Activated Protein Kinase in Tumor Cells Adapted to Low pH
Erin E. Mendoza et al.
TRANSLATIONAL ONCOLOGY (2012)
Deconvoluting the context-dependent role for autophagy in cancer
Eileen White
NATURE REVIEWS CANCER (2012)
Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 in prostate cancer cells
Jong-Seok Moon et al.
BIOCHEMICAL JOURNAL (2011)
Metformin and the Incidence of Prostate Cancer in Patients with Type 2 Diabetes
Laurent Azoulay et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2011)
CaM Kinase Kinase β-Mediated Activation of the Growth Regulatory Kinase AMPK Is Required for Androgen-Dependent Migration of Prostate Cancer Cells
Daniel E. Frigo et al.
CANCER RESEARCH (2011)
Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1
Isaam Ben Sahra et al.
CANCER RESEARCH (2011)
PGC1α Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis
Kavita Bhalla et al.
CANCER RESEARCH (2011)
AMPK-mediated autophagy is a survival mechanism in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia
Rishi Raj Chhipa et al.
CELLULAR SIGNALLING (2011)
C11-Acetate and F-18 FDG PET for Men With Prostate Cancer Bone Metastases Relative Findings and Response to Therapy
Evan Y. Yu et al.
CLINICAL NUCLEAR MEDICINE (2011)
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
Charles E. Massie et al.
EMBO JOURNAL (2011)
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
Kathrin Zaugg et al.
GENES & DEVELOPMENT (2011)
Chemical Genetic Screen for AMPKα2 Substrates Uncovers a Network of Proteins Involved in Mitosis
Max R. Banko et al.
MOLECULAR CELL (2011)
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
Maria M. Mihaylova et al.
NATURE CELL BIOLOGY (2011)
Integrative Genomic Profiling of Human Prostate Cancer
Barry S. Taylor et al.
CANCER CELL (2010)
Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
Simon A. Hawley et al.
CELL METABOLISM (2010)
Survival advantage of AMPK activation to androgen-independent prostate cancer cells during energy stress
Rishi Raj Chhipa et al.
CELLULAR SIGNALLING (2010)
Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes - ZODIAC-16
Gijs W. D. Landman et al.
DIABETES CARE (2010)
Long-Term Metformin Use Is Associated With Decreased Risk of Breast Cancer
Michael Bodmer et al.
DIABETES CARE (2010)
Molecular genetics of prostate cancer: new prospects for old challenges
Michael M. Shen et al.
GENES & DEVELOPMENT (2010)
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
Marc Foretz et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation
Atsushi Nakano et al.
NATURE CELL BIOLOGY (2010)
β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)
Jonathan S. Oakhill et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
New Prospective for Non-Invasive Detection,Grading, Size Evaluation, and Tumor Location of Prostate Cancer
M. Cortesi et al.
PROSTATE (2010)
Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation
David Bungard et al.
SCIENCE (2010)
Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells
H. L. Bennett et al.
CELL DEATH & DISEASE (2010)
3,3 '-Diindolylmethane induces a G(1) arrest in human prostate cancer cells irrespective of androgen receptor and p53 status
Omar I. Vivar et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Proline Oxidase Functions as a Mitochondrial Tumor Suppressor in Human Cancers
Yongmin Liu et al.
CANCER RESEARCH (2009)
The active form of the metabolic sensor AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis
Alejandro Vazquez-Martin et al.
CELL CYCLE (2009)
New Users of Metformin Are at Low Risk of Incident Cancer A cohort study among people with type 2 diabetes
Gillian Libby et al.
DIABETES CARE (2009)
TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells
Griselda Herrero-Martin et al.
EMBO JOURNAL (2009)
Down-regulation of AMP-activated protein kinase sensitizes DU145 carcinoma to Fas-induced apoptosis via c-FLIP degradation
Seung-Nam Jung et al.
EXPERIMENTAL CELL RESEARCH (2009)
Molecular mechanisms of castration-resistant prostate cancer progression
Smitha S. Dutt et al.
FUTURE ONCOLOGY (2009)
AMP-activated protein kinase phosphorylates glutamine : fructose-6-phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity
Satoshi Eguchi et al.
GENES TO CELLS (2009)
Regulation and Function of Proline Oxidase Under Nutrient Stress
Jui Pandhare et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
2-18F-Fluoropropionic Acid as a PET Imaging Agent for Prostate Cancer
Naga VaraKishore Pillarsetty et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
AMP-activated protein kinase promotes human prostate cancer cell growth and survival
Hyeon Ung Park et al.
MOLECULAR CANCER THERAPEUTICS (2009)
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Carles Canto et al.
NATURE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic
Kei Sakamoto et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
Xu Huang et al.
BIOCHEMICAL JOURNAL (2008)
Lkb1 deficiency causes prostate neoplasia in the mouse
Helen B. Pearson et al.
CANCER RESEARCH (2008)
Differential effects of resveratrol on androgen-responsive LNCaP human prostate cancer cells in vitro and in vivo
Thomas T. Y. Wang et al.
CARCINOGENESIS (2008)
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
Ralph J. DeBerardinis et al.
CELL METABOLISM (2008)
AMP-activated protein kinase phosphorylates transcription factors of the CREB family
D. M. Thomson et al.
JOURNAL OF APPLIED PHYSIOLOGY (2008)
A Genecentric Human Protein Atlas for Expression Profiles Based on Antibodies
Lisa Berglund et al.
MOLECULAR & CELLULAR PROTEOMICS (2008)
AMPK phosphorylation of raptor mediates a metabolic checkpoint
Dana M. Gwinn et al.
MOLECULAR CELL (2008)
Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers
Y. Liu et al.
ONCOGENE (2008)
FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells
A. N. Cornforth et al.
ONCOGENE (2008)
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
I. Ben Sahra et al.
ONCOGENE (2008)
AMP-activated protein kinase phosphorylates Golgi-specific brefeldin A resistance factor 1 at Thr1337 to induce disassembly of Golgi apparatus
Takafumi Miyamoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Transcriptional profiling of transurethral resection samples provides insight into molecular mechanisms of hormone refractory prostate cancer
O. Stoss et al.
PROSTATE CANCER AND PROSTATIC DISEASES (2008)
A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome
M. Sanchez-Cespedes
ONCOGENE (2007)
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
Eric L. Greer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
被撤回的出版物: Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner (Retracted article. See vol. 142, 2020)
Ping Song et al.
CIRCULATION (2007)
Deletion of a small consensus region at 6q15, including the MAP3K7 gene, is significantly associated with high-grade prostate cancers
Wennuan Liu et al.
CLINICAL CANCER RESEARCH (2007)
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
Sibylle Jaeger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794
Alexandros Tzatsos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The energy sensing LKB1-AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
Jiyong Liang et al.
NATURE CELL BIOLOGY (2007)
A pivotal role for endogenous TGF-β-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway
Min Xie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Androgen activation of the sterol regulatory element-binding protein pathway: Current insights
Hannelore V. Heemers et al.
MOLECULAR ENDOCRINOLOGY (2006)
Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins
Youyuan Xu et al.
CANCER RESEARCH (2006)
Increased lipogenesis in cancer cells: new players, novel targets
Johannes V. Swinnen et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2006)
5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments
Keith R. Laderoute et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Regular use of aspirin and prostate cancer risk (United States)
RJ Menezes et al.
CANCER CAUSES & CONTROL (2006)
Altered metabolism and mitochondrial genome in prostate cancer
GD Dakubo et al.
JOURNAL OF CLINICAL PATHOLOGY (2006)
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
SH Koo et al.
NATURE (2005)
Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer
H Bando et al.
CLINICAL CANCER RESEARCH (2005)
The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases
RL Hurley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes
H Mehenni et al.
HUMAN MOLECULAR GENETICS (2005)
Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
A Woods et al.
CELL METABOLISM (2005)
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
SA Hawley et al.
CELL METABOLISM (2005)
Mitochondrial function, zinc, and intermediary metabolism relationships in normal prostate and prostate cancer
LC Costello et al.
MITOCHONDRION (2005)
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
RG Jones et al.
MOLECULAR CELL (2005)
被撤回的出版物: Glucose deprivation increases mRNA stability of vascular endothelial growth factor through activation of AMP-activated protein kinase in DU145 prostate carcinoma (Retracted article. See vol. 293, pg. 18014, 2018)
H Yun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms
XQ Xiang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
TSC2 mediates cellular energy response to control cell growth and survival
K Inoki et al.
CELL (2003)
Genetic mapping of allelic loss on chromosome 6q within heterogeneous prostate carcinoma
N Konishi et al.
CANCER SCIENCE (2003)
Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase
DG Hardie et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2002)
The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase
AS Marsin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
STO-609, a specific inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase
H Tokumitsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulation of transcription by AMP-activated protein kinase - Phosphorylation of p300 blocks its interaction with nuclear receptors
WB Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Hepatocyte nuclear factor-4α involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase
I Leclerc et al.
DIABETES (2001)
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
AS Marsin et al.
CURRENT BIOLOGY (2000)
Effect of anti-inflammatory drugs on overall risk of common cancer: case-control study in general practice research database
MJS Langman et al.
BRITISH MEDICAL JOURNAL (2000)
分享论文
