期刊
ANALYTICAL METHODS
卷 10, 期 21, 页码 2450-2455出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ay00677f
关键词
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资金
- Project of Wenzhou Science & Technology Bureau [W20170006, S20150012]
- Opening Project of Zhejiang Provincial Top Key Discipline of Pharmaceutical Sciences [201712]
- Science and Technology Research Program of Chongqing Municipal Education Commission [KJ1601404, KJ1706156]
- Open Project of State Key Laboratory Cultivation Base for Nonmetal Composites and Functional Materials [17kffk06]
- Scientific Research Program of Chongqing University of Education [KY201550C]
- Program of Innovation Center of Lipid Resources and Children's Daily Chemicals at Chongqing University of Education [2017XJPT01]
Herein, a fast and visible colorimetric method for bisphenol A (BPA) detection was developed using hemin-functionalized reduced graphene oxide (H-rGO) composites and aptamer. The aptamer can be stably adsorbed on the surface of H-rGO, preventing H-rGO from salt-induced aggregation. However, in the presence of BPA, the aptamer can bind with BPA; this results in the aggregation of H-rGO. Consequently, the supernatant contains a little H-rGO and shows light blue color after the chromogenic reaction. The color difference can be used for the quantitative detection of BPA. The designed aptasensor displayed a linear response for BPA in the range from 5 nM to 100 nM with a detection limit of 2 nM. This colorimetric aptasensing platform offered great advantages, including label-free conditions and visible result readout platform, for quick screening of BPA for on-site analysis and in-house diagnosis.
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