4.5 Article

Quack: A quality assurance tool for high throughput sequence data

期刊

ANALYTICAL BIOCHEMISTRY
卷 548, 期 -, 页码 38-43

出版社

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ab.2018.01.028

关键词

Quality assurance; Visualization; FASTQ; Quality check; DNA

资金

  1. USDA ARS award [58-6066-6-059, 58-6066-6-046]

向作者/读者索取更多资源

The quality of data generated by high-throughput DNA sequencing tools must be rapidly assessed in order to determine how useful the data may be in making biological discoveries; higher quality data leads to more confident results and conclusions. Due to the ever-increasing size of data sets and the importance of rapid quality assessment, tools that analyze sequencing data should quickly produie easily interpretable graphics. Quack addresses these issues by generating information-dense visualizations from FASTQ files at a speed far surpassing other publicly available quality assurance tools in a manner independent of sequencing technology.

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