4.5 Review

Whole animal HTS of small molecules for antifungal compounds

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes

Stuart L. Schreiber et al.

Article Chemistry, Multidisciplinary

The discovery of novel antifungal scaffolds by structural simplification of the natural product sampangine

Zhigan Jiang et al.

CHEMICAL COMMUNICATIONS (2015)

Article Biochemistry & Molecular Biology

Discovery of highly potent triazole antifungal agents with piperidine-oxadiazole side chains

Xiaomeng He et al.

MEDCHEMCOMM (2015)

Article Immunology

A Multi-Host Approach for the Systematic Analysis of Virulence Factors in Cryptococcus neoformans

Athanasios Desalermos et al.

JOURNAL OF INFECTIOUS DISEASES (2015)

Review Biochemistry & Molecular Biology

Caenorhabditis elegans: A Model System for Anti-Cancer Drug Discovery and Therapeutic Target Identification

Robert A. Kobetl et al.

BIOMOLECULES & THERAPEUTICS (2014)

Review Infectious Diseases

Echinocandins in the treatment of candidaemia and invasive candidiasis: clinical and economic perspectives

Chin Fen Neoh et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2014)

Article Medicine, General & Internal

Multistate Point- Prevalence Survey of Health Care- Associated Infections

Shelley S. Magill et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Parasitology

Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics

Steven D. Buckingham et al.

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE (2014)

Article Pharmacology & Pharmacy

Caenorhabditis elegans-based Model Systems for Antifungal Drug Discovery

Cleo G. Anastassopoulou et al.

CURRENT PHARMACEUTICAL DESIGN (2012)

Article Biochemical Research Methods

An image analysis toolbox for high-throughput C. elegans assays

Carolina Wahlby et al.

NATURE METHODS (2012)

Review Pharmacology & Pharmacy

Using Caenorhabditis elegans for antimicrobial drug discovery

Athanasios Desalermos et al.

EXPERT OPINION ON DRUG DISCOVERY (2011)

Article Multidisciplinary Sciences

Antifungal Activity of Microbial Secondary Metabolites

Jeffrey J. Coleman et al.

PLOS ONE (2011)

Article Biochemistry & Molecular Biology

Characterization of Plant-Derived Saponin Natural Products against Candida albicans

Jeffrey J. Coleman et al.

ACS CHEMICAL BIOLOGY (2010)

Review Infectious Diseases

Invasive fungal infections in congenital immunodeficiencies

C. Antachopoulos

CLINICAL MICROBIOLOGY AND INFECTION (2010)

Review Microbiology

Epidemiology of Invasive Mycoses in North America

Michael A. Pfaller et al.

CRITICAL REVIEWS IN MICROBIOLOGY (2010)

Review Biochemistry & Molecular Biology

Natural products as antifungal agents against clinically relevant pathogens

Roberto Di Santo

NATURAL PRODUCT REPORTS (2010)

News Item Biochemistry & Molecular Biology

Know your chemical space

Andrew L. Hopkins et al.

NATURE CHEMICAL BIOLOGY (2010)

Review Biotechnology & Applied Microbiology

An insight into the antifungal pipeline: selected new molecules and beyond

Luis Ostrosky-Zeichner et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

Article Biochemistry & Molecular Biology

WormBase: a comprehensive resource for nematode research

Todd W. Harris et al.

NUCLEIC ACIDS RESEARCH (2010)

Editorial Material Immunology

From the outside in and the inside out Antifungal immune responses in Caenorhabditis elegans

Read Pukkila-Worley et al.

VIRULENCE (2010)

Article Biochemistry & Molecular Biology

High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model

Terence I. Moy et al.

ACS CHEMICAL BIOLOGY (2009)

Review Biochemistry & Molecular Biology

Antifungal Drug Discovery through the Study of Invertebrate Model Hosts

R. Pukkila-Worley et al.

CURRENT MEDICINAL CHEMISTRY (2009)

Review Microbiology

Efflux in Fungi: La Piece de Resistance

Jeffrey J. Coleman et al.

PLOS PATHOGENS (2009)

Review Infectious Diseases

Changing epidemiology of systemic fungal infections

M. Richardson et al.

CLINICAL MICROBIOLOGY AND INFECTION (2008)

Article Biochemical Research Methods

A C. elegans-based, whole animal, in vivo screen for the identification of antifungal compounds

Emmanouil Tampakakis et al.

NATURE PROTOCOLS (2008)

Review Infectious Diseases

Recent advances in antifungal chemotherapy

George Petrikkos et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2007)

Review Microbiology

Using non-mammalian hosts to study fungal virulence and host defense

Beth Burgwyn Fuchs et al.

CURRENT OPINION IN MICROBIOLOGY (2006)

Article Multidisciplinary Sciences

Identification of novel antimicrobials using a live-animal infection model

Terence I. Moy et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Biotechnology & Applied Microbiology

The pursuit of cryptococcal pathogenesis: heterologous hosts and the study of cryptococcal host-pathogen interactions

Roanna London et al.

FEMS YEAST RESEARCH (2006)

Review Pharmacology & Pharmacy

Newer triazole antifungal agents: pharmacology, spectrum, clinical efficacy and limitations

George Aperis et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2006)

Article Biochemistry & Molecular Biology

Drug discovery: Here comes the worm

Laurent Segalat

ACS CHEMICAL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

The worm has turned -: microbial virulence modeled in Caenorhabditis elegans

CD Sifri et al.

TRENDS IN MICROBIOLOGY (2005)

Article Pharmacology & Pharmacy

The nematode Caenorhabditis elegans as a model of organophosphate-induced mammalian neurotoxicity

RD Cole et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)

Article Biochemistry & Molecular Biology

WormBase as an integrated platform for the C-elegans ORFeome

NS Chen et al.

GENOME RESEARCH (2004)

Article Biology

Food transport in the C-elegans pharynx

L Avery et al.

JOURNAL OF EXPERIMENTAL BIOLOGY (2003)

Review Immunology

Antifungal drug resistance

J Loeffler et al.

CLINICAL INFECTIOUS DISEASES (2003)

Article Multidisciplinary Sciences

A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity

DH Kim et al.

SCIENCE (2002)

Review Microbiology

Caenorhabditis elegans as a host for the study of host-pathogen interactions

A Aballay et al.

CURRENT OPINION IN MICROBIOLOGY (2002)

Article Multidisciplinary Sciences

A simple model host for identifying Gram-positive virulence factors

DA Garsin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Letter Immunology

Estimating the cost of nosocomial candidemia in the United States

LG Miller et al.

CLINICAL INFECTIOUS DISEASES (2001)