期刊
ANALYTICA CHIMICA ACTA
卷 1033, 期 -, 页码 180-184出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2018.05.065
关键词
Formaldehyde; Pyrene; Fluorescence; Probe; Turn-on
资金
- Science-Technology Foundation for Outstanding Young Scientists of Henan Academy of Agricultural Sciences [2016YQ22]
- Special Foundation for Research and Development of Henan Academy of Agricultural Sciences [YNK 20177517, 20177510, 201710609]
- Research Program of Foundation and Advanced Technology of Henan Province [152300410144]
A novel and simple pyrene-based fluorescent probe (B1) was synthesized and used for the detection of formaldehyde (FA). When B1 was added to FA in CH3CH2OH/HEPES (10 mM, pH = 7.4, 1:99, v/v) solution, the solution system strongly enhanced the fluorescence. Over various small molecular species, probe B1 showed high sensitivity and selectivity for detecting FA, with a low limit of detection (0.107 mu M). Furthermore, probe B1 was successfully applied for visualizing FA in human embryonic kidney (HEK293T) cells, demonstrating its value of application in living biomedical samples. (C) 2018 Elsevier B.V. All rights reserved.
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