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Diagnosing gastrointestinal stromal tumours by single photon emission computed tomography using nano-radiopharmaceuticals based on bevacizumab monoclonal antibody

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IOP PUBLISHING LTD
DOI: 10.1088/2057-1976/2/4/045017

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radiopharmaceuticals; nano-radiopharmaceuticals; cancer; nuclear medicine

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The use of nanoparticles is increasing each day. Although only a few nanoparticle drugs are on the market, their research and development are immense. In the field of cancer, the number of new drugs is very large, however, the efficacies of those drugs are very limited. In this study we developed a new radioactive nanoparticle for gastrointestinal stromal tumour imaging and early detection. The results suggest that this nanoparticle may be used for imaging as well as for treatment due the efficacy and inherent quality of nanoparticle systems, especially regarding the higher enhanced permeability and retention effect.

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