期刊
ALZHEIMER DISEASE & ASSOCIATED DISORDERS
卷 32, 期 1, 页码 10-17出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/WAD.0000000000000223
关键词
dementia; neuropsychological test; cognition; UDS
资金
- NIA/NIH [U01 AG016976]
- NIA [P30 AG019610, P30 AG013846, P50 AG008702, P50 AG025688, P50 AG047266, P30 AG010133, P50 AG005146, P50 AG005134]
- Takeda Pharmaceutical Company
- Eli Lilly/Avid Radiopharmaceuticals
- NIH [P50 AG005681, P01AG003991, P01AG026276, UF01AG032438]
- [P50 AG016574]
- [P50 AG005138]
- [P30 AG008051]
- [P30 AG013854]
- [P30 AG008017]
- [P30 AG010161]
- [P50 AG047366]
- [P30 AG010129]
- [P50 AG016573]
- [P50 AG005131]
- [P50 AG023501]
- [P30 AG035982]
- [P30 AG028383]
- [P30 AG053760]
- [P30 AG010124]
- [P50 AG005133]
- [P50 AG005142]
- [P30 AG012300]
- [P30 AG049638]
- [P50 AG005136]
- [P50 AG033514]
- [P50 AG047270]
- NATIONAL INSTITUTE ON AGING [P50AG047266, P30AG010129, P30AG049638, P30AG010133, P30AG035982, P50AG005131, P50AG047366, P30AG012300, P30AG010124, U01AG016976, P50AG005134, P50AG005142, P50AG025688, P50AG008702, P30AG053760, P50AG005138, P50AG047270, P30AG008051, P50AG005146, P50AG016574, P30AG008017, P50AG016573, P50AG005133, P30AG019610, U01AG032438, P30AG013854, P50AG005681, P30AG010161, P50AG023501, P50AG005136, P30AG028383, P50AG033514, P01AG003991, P01AG026276, P30AG062429, P30AG013846] Funding Source: NIH RePORTER
Introduction:The neuropsychological battery of the Uniform Data Set (UDSNB) was implemented in 2005 by the National Institute on Aging (NIA) Alzheimer Disease Centers program to measure cognitive performance in dementia and mild cognitive impairment due to Alzheimer Disease. This paper describes a revision, the UDSNB 3.0.Methods:The Neuropsychology Work Group of the NIA Clinical Task Force recommended revisions through a process of due diligence to address shortcomings of the original battery. The UDSNB 3.0 covers episodic memory, processing speed, executive function, language, and constructional ability. Data from 3602 cognitively normal participants in the National Alzheimer Coordinating Center database were analyzed.Results:Descriptive statistics are presented. Multivariable linear regression analyses demonstrated score differences by age, sex, and education and were also used to create a normative calculator available online.Discussion:The UDSNB 3.0 neuropsychological battery provides a valuable non proprietary resource for conducting research on cognitive aging and dementia.
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