期刊
RSC ADVANCES
卷 6, 期 68, 页码 63933-63939出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra13565j
关键词
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资金
- JSPS Bilateral Joint Research Projects (Japan-Czech Republic)
- JST Visegrad Group (V4)-Japan Joint Research Project on Advanced Materials
- KAKENHI [16H03828]
- [26-3120]
- Grants-in-Aid for Scientific Research [16H03828, 14J03120] Funding Source: KAKEN
Silicon quantum dots (Si-QDs) dispersible in water and exhibiting bright near infrared (NIR) luminescence are a very attractive nano-light-emitter usable in bioimaging and biosensing. Here, we demonstrate the fabrication of NIR luminescent nanocomposites composed of Si-QDs and gold nanoparticles (Au-NPs) by DNA hybridization. We first develop processes to functionalize the surface of Si-QDs with different types of silane coupling agents without notably affecting the water solubility and the luminescence properties, and then conjugate the functionalized Si-QDs with single-stranded DNA (ssDNA). DNA hybridization with a Au-NP with complementary ssDNA results in the formation of Si-QDs/Au-NP nanocomposites.
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