期刊
AMERICAN JOURNAL OF CLINICAL NUTRITION
卷 103, 期 2, 页码 389-397出版社
AMER SOC NUTRITION-ASN
DOI: 10.3945/ajcn.115.118612
关键词
protein; growth; BMI; weaning; children; longitudinal studies; macronutrients; obesity
资金
- UK Medical Research Council [U105960389]
- MRC
- Cancer Research UK [C1418/A7974]
- Danone Baby Nutrition
- Cancer Research UK [14133] Funding Source: researchfish
- Medical Research Council [1197514, MC_U105960389] Funding Source: researchfish
- MRC [MC_U105960389] Funding Source: UKRI
Background: Few large epidemiologic studies have investigated the role of postweaning protein intake in excess weight and adiposity of young children, despite children in the United Kingdom consistently consuming protein in excess of their physiologic requirements. Objective: We investigated whether a higher proportion of protein intake from energy beyond weaning is associated with greater weight gain, higher body mass index (BMI), and risk of overweight or obesity in children up to 5 y of age. Design: Participants were 2154 twins from the Gemini cohort. Dietary intake was collected by using a 3-d diet diary when the children had a mean age of 21 mo. Weight and height were collected every 3 mo, from birth to 5 y. Longitudinal models investigated associations of protein intake with BMI, weight, and height, with adjustment for age at diet diary, sex, total energy intake, birth weight/length, and rate of prior growth and clustering within families. Logistic regression investigated protein intake in relation to the odds of overweight or obesity at 3 and 5 y of age. Results: A total of 2154 children had a mean +/- SD of 5.7 +/- 3.2 weight and height measurements up to 5 y. Total energy from protein was associated with higher BMI (beta = 0.043; 95% CI: 0.011, 0.075) and weight (beta = 0.052; 95% CI: 0.031, 0.074) but not height (beta = 0.088; 95% CI: 0.038, 0.213) between 21 mo and 5 y. Substituting percentage energy from fat or carbohydrate for percentage energy from protein was associated with decreases in BMI and weight. Protein intake was associated with a trend in increased odds of overweight or obesity at 3 y (OR = 1.10; 95% CI 0.99, 1.22, P = 0.075), but the effect was not statistically significant at 5 y. Conclusion: A higher proportion of energy from protein during the complementary feeding stage is associated with greater increases in weight and BMI in early childhood in this large cohort of United Kingdom children.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据