期刊
JOURNAL OF FUNCTIONAL BIOMATERIALS
卷 7, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/jfb7030018
关键词
tissue engineering; mechanical properties; scaffold design; scaffold fabrication; biomaterials; nanodiamond; hydroxyapatite; bioactive glass particles; silver nanoparticles; surface coating
资金
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- University of Saskatchewan
Mechanical properties of a scaffold play an important role in its in vivo performance in bone tissue engineering, due to the fact that implanted scaffolds are typically subjected to stress including compression, tension, torsion, and shearing. Unfortunately, not all the materials used to fabricate scaffolds are strong enough to mimic native bones. Extensive research has been conducted in order to increase scaffold strength and mechanical performance by incorporating nanoparticles and/or coatings. An incredible improvement has been achieved; and some outstanding examples are the usage of nanodiamond, hydroxyapatite, bioactive glass particles, SiO2, MgO, and silver nanoparticles. This review paper aims to present the results, to summarize significant findings, and to give perspective for future work, which could be beneficial to future bone tissue engineering.
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