4.7 Article

Recent developments in dopamine-based materials for cancer diagnosis and therapy

期刊

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.cis.2018.01.001

关键词

Polydopamine; Nanomaterials; Biosensing; Bioimaging; Cancer therapy

资金

  1. National Natural Science Foundation of China [21703169, 21773183, 21603138, 21505103, 21503236, 21320102004]
  2. Scientific Research Program - Shaanxi Provincial Education Department [17JK0600]
  3. Scientific Research Plan of Shaanxi Province of China [2017JQ2024, 2016KJXX-16]

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Dopamine-based materials are emerging as novel biomaterials and have attracted considerable interests in the fields of biosensing, bioimaging and cancer therapy due to their unique physicochemical properties, such as versatile adhesion property, high chemical reactivity, excellent biocompatibility and biodegradability, strong photothermal conversion capacity, etc. In this review, we present an overview of recent research progress on dopamine-based materials for diagnosis and therapy of cancer. The review starts with a summary of the physicochemical properties of dopamine-based materials in general. Then detailed description is followed on their applications in the fields of diagnosis and treatment of cancers. The review concludes with an outline of some remaining challenges for dopamine-based materials to be used for clinical applications. (C) 2018 Elsevier B.V. All rights reserved.

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