3.8 Article

Successful management of zinc phosphide poisoning

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INDIAN JOURNAL OF CRITICAL CARE MEDICINE
卷 20, 期 6, 页码 368-370

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MEDKNOW PUBLICATIONS & MEDIA PVT LTD
DOI: 10.4103/0972-5229.183907

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Management; poisoning; zinc phosphide

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Zinc phosphide (Zn2P3) rodenticide, is generally misused intentionally for suicidal purpose in Iran. For many years, scientists believe that liberation of phosphine (PH3) on contact with acidic content of the stomach is responsible for clinical presentations. However, relatively long time interval between ingestion of Zn2P3 and presentation of its systemic toxicity, and progression of acute liver failure could not be explained by the current opinion. Hence, an innovative theory intended that phosphonium, as an intermediate product will create and pass through the stomach, which then will reduce to produce PH3 in the luminal tract. Here, we present a case of massive Zn2P3 poisoning. In our case, we used repeated doses of castor oil to induce bowel movement with an aim of removing unabsorbed toxin, which was proved by radiography. Interestingly, the patient presents only mild symptoms of toxicity such as transient metabolic acidosis and hepatic dysfunction.

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