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JOURNAL OF CONTROLLED RELEASE (2010)
Lipid-based nanotherapeutics for siRNA delivery
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JOURNAL OF INTERNAL MEDICINE (2010)
Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
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LANCET (2010)
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NATURE BIOTECHNOLOGY (2010)
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NATURE MATERIALS (2010)
Therapeutic cell engineering with surface-conjugated synthetic nanoparticles
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NATURE MEDICINE (2010)
Lipid-like materials for low-dose, in vivo gene silencing
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Exposure to Titanium Dioxide Nanomaterials Provokes Inflammation of an in Vitro Human Immune Construct
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ACS NANO (2009)
Impact of Nanotechnology on Drug Delivery
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ACS NANO (2009)
Synthesis of Functional Polymers by Post-Polymerization Modification
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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Drug Delivery by an Enzyme-Mediated Cyclization of a Lipid Prodrug with Unique Bilayer-Formation Properties
Lars Linderoth et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
The Inflammasomes: Guardians of the Body
Fablo Martinon et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Cell-controlled and spatially arrayed gene delivery from fibrin hydrogels
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BIOMATERIALS (2009)
Reduction-sensitive polymers and bioconjugates for biomedical applications
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BIOMATERIALS (2009)
Bioapplications of RAFT Polymerization
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CHEMICAL REVIEWS (2009)
Anti-inflammatory and pro-inflammatory roles of TGF-β, IL-10, and IL-22 in immunity and autoimmunity
Shomyseh Sanjabi et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
Oral osmotically driven systems: 30 years of development and clinical use
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EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2009)
Expansile Nanoparticles: Synthesis, Characterization, and in Vivo Efficacy of an Acid-Responsive Polymeric Drug Delivery System
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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Antibody-Mediated Targeting of siRNA via the Human Insulin Receptor Using Avidin-Biotin Technology
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MOLECULAR PHARMACEUTICS (2009)
A Novel Mechanism Is Involved in Cationic Lipid-Mediated Functional siRNA Delivery
James J. Lu et al.
MOLECULAR PHARMACEUTICS (2009)
Protein Nanocapsule Weaved with Enzymatically Degradable Polymeric Network
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NANO LETTERS (2009)
A Magnetically Triggered Composite Membrane for On-Demand Drug Delivery
Todd Hoare et al.
NANO LETTERS (2009)
Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis
Matthew Spite et al.
NATURE (2009)
Materials engineering for immunomodulation
Jeffrey A. Hubbell et al.
NATURE (2009)
Organic electronics for precise delivery of neurotransmitters to modulate mammalian sensory function
Daniel T. Simon et al.
NATURE MATERIALS (2009)
Infection-mimicking materials to program dendritic cells in situ
Omar A. Ali et al.
NATURE MATERIALS (2009)
Knocking down barriers: advances in siRNA delivery
Kathryn A. Whitehead et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
Jesper B. Bramsen et al.
NUCLEIC ACIDS RESEARCH (2009)
PEG Hydrogels for the Controlled Release of Biomolecules in Regenerative Medicine
Chien-Chi Lin et al.
PHARMACEUTICAL RESEARCH (2009)
Formulation and Pharmacokinetics of Self-Assembled Rifampicin Nanoparticle Systems for Pulmonary Delivery
Jean C. Sung et al.
PHARMACEUTICAL RESEARCH (2009)
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
Fiona A. Sharp et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
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SCIENCE (2009)
In Situ Regulation of DC Subsets and T Cells Mediates Tumor Regression in Mice
Omar A. Ali et al.
SCIENCE TRANSLATIONAL MEDICINE (2009)
Systems medicine: the future of medical genomics and healthcare
Charles Auffray et al.
GENOME MEDICINE (2009)
Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: A 10-year institutional experience
Frank J. Attenello et al.
ANNALS OF SURGICAL ONCOLOGY (2008)
Dissolving microneedles for transdermal drug delivery
Jeong W. Lee et al.
BIOMATERIALS (2008)
On the mechanisms of biocompatibility
David F. Williams
BIOMATERIALS (2008)
Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein(a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein(a) transgenic mice
Esther Merki et al.
CIRCULATION (2008)
The origins and evolution of controlled drug delivery systems
Allan S. Hoffman
JOURNAL OF CONTROLLED RELEASE (2008)
Efficient in vivo delivery of siRNA to the liver by conjugation of α-tocopherol
Kazutaka Nishina et al.
MOLECULAR THERAPY (2008)
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
Stephanie C. Eisenbarth et al.
NATURE (2008)
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
Akin Akinc et al.
NATURE BIOTECHNOLOGY (2008)
Transdermal drug delivery
Mark R. Prausnitz et al.
NATURE BIOTECHNOLOGY (2008)
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
Veit Hornung et al.
NATURE IMMUNOLOGY (2008)
Hydrogels in drug delivery: Progress and challenges
Todd R. Hoare et al.
POLYMER (2008)
Foreign body reaction to biomaterials
James M. Anderson et al.
SEMINARS IN IMMUNOLOGY (2008)
The challenge of drugging undruggable targets in cancer: Lessons learned from targeting BCL-2 family members
Gregory L. Verdine et al.
CLINICAL CANCER RESEARCH (2007)
Introduction of zwitterionic motifs into bacterial polysaccharides generates TLR2 agonists able to activate APCs
Simona Gallorini et al.
JOURNAL OF IMMUNOLOGY (2007)
Nanocarriers as an emerging platform for cancer therapy
Dan Peer et al.
NATURE NANOTECHNOLOGY (2007)
Wear particles, periprosthetic osteolysis and the immune system
Stuart B. Goodman
BIOMATERIALS (2007)
Remotely triggered release from magnetic nanoparticles
Austin M. Derfus et al.
ADVANCED MATERIALS (2007)
Current ceramic materials and systems with clinical recommendations: A systematic review
Heather J. Conrad et al.
JOURNAL OF PROSTHETIC DENTISTRY (2007)
Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity
Sterghios Athanasios Moschos et al.
BIOCONJUGATE CHEMISTRY (2007)
Magnetic nanoparticles for drug delivery
Manuel Arruebo et al.
NANO TODAY (2007)
Biocompatibility of polypyrrole particles: an in-vivo study in mice
Almira Ramanaviciene et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2007)
Living ring-opening metathesis polymerization
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PROGRESS IN POLYMER SCIENCE (2007)
Inhaling medicines: delivering drugs to the body through the lungs
John S. Patton et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Lipid-based nanoparticles for nucleic acid delivery
Weijun Li et al.
PHARMACEUTICAL RESEARCH (2007)
Thermo- and pH-responsive polymers in drug delivery
Dirk Schmaljohann
ADVANCED DRUG DELIVERY REVIEWS (2006)
RNA interference in vitro and in vivo using a chitosan/siRNA nanoparticle system
Kenneth A. Howard et al.
MOLECULAR THERAPY (2006)
Photocleavage of o-nitrobenzyl ether derivatives for rapid biomedical release applications
Moon Suk Kim et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Hydrogels in biology and medicine: From molecular principles to bionanotechnology
Nicholas A. Peppas et al.
ADVANCED MATERIALS (2006)
Oligonucleotide-modified gold nanoparticles for intracellular gene regulation
NL Rosi et al.
SCIENCE (2006)
Electrically controlled drug delivery from biotin-doped conductive polypyrrole
PM George et al.
ADVANCED MATERIALS (2006)
Electrochemically controlled release of dexamethasone from conducting polymer polypyrrole coated electrode
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JOURNAL OF CONTROLLED RELEASE (2006)
Conducting-polymer nanotubes for controlled drug release
MR Abidian et al.
ADVANCED MATERIALS (2006)
Enzyme-responsive materials: a new class of smart biomaterials
Rein V. Ulijn
JOURNAL OF MATERIALS CHEMISTRY (2006)
High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation
YB Zhao et al.
MOLECULAR THERAPY (2006)
The SIRP family of receptors and immune regulation
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NATURE REVIEWS IMMUNOLOGY (2006)
Differential levels of dendritic cell maturation on different biomaterials used in combination products
JE Babensee et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2005)
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
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NATURE BIOTECHNOLOGY (2005)
Suppression of RNA recognition by Toll-like receptors:: The impact of nucleoside modification and the evolutionary origin of RNA
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IMMUNITY (2005)
Positional effect of chemical modifications on short interference RNA activity in mammalian cells
TP Prakash et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Biodegradable polymer microneedles: Fabrication, mechanics and transdermal drug delivery
JH Park et al.
JOURNAL OF CONTROLLED RELEASE (2005)
Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection efficiency
IS Zuhorn et al.
MOLECULAR THERAPY (2005)
Physical methods for gene transfer: Improving the kinetics of gene delivery into cells
S Mehier-Humbert et al.
ADVANCED DRUG DELIVERY REVIEWS (2005)
Relaxational behavior and swelling-pH master curves of poly[(diethylaminoethyl methacrylate)-graft-(ethylene glycol)] hydrogels
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POLYMER INTERNATIONAL (2005)
Innovation - Healing sound: the use of ultrasound in drug delivery and other therapeutic applications
S Mitragotri
NATURE REVIEWS DRUG DISCOVERY (2005)
Cancer nanotechnology: Opportunities and challenges
M Ferrari
NATURE REVIEWS CANCER (2005)
Stimuli responsive polymers for biomedical applications
CDH Alarcón et al.
CHEMICAL SOCIETY REVIEWS (2005)
Recent advances with liposomes as pharmaceutical carriers
VP Torchilin
NATURE REVIEWS DRUG DISCOVERY (2005)
Drug delivery systems: Entering the mainstream
TM Allen et al.
SCIENCE (2004)
Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression
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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Glutathione metabolism and its implications for health
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JOURNAL OF NUTRITION (2004)
Oxidation-responsive polymeric vesicles
A Napoli et al.
NATURE MATERIALS (2004)
Current status and future potential of transdermal drug delivery
MR Prausnitz et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
Pattern of recurrence following local chemotherapy with biodegradable carmustine (BCNU) implants in patients with glioblastoma
A Giese et al.
JOURNAL OF NEURO-ONCOLOGY (2004)
Controlled structure and properties of thermoresponsive nanoparticle-hydrogel composites
C Wang et al.
ADVANCED MATERIALS (2004)
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
J Soutschek et al.
NATURE (2004)
Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells
C Lorenz et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Stimuli-responsive conjugated copolymers having electro-active azulene and bithiophene units in the polymer skeleton: Effect of protonation and p-doping on conducting properties
FK Wang et al.
MACROMOLECULES (2004)
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J Kopecek
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
siRNA function in RNAi: A chemical modification analysis
YL Chiu et al.
RNA (2003)
Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles
JL Bourges et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Advances in biomaterials, drug delivery, and bionanotechnology
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AICHE JOURNAL (2003)
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery
DG Anderson et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
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DRUG DISCOVERY TODAY (2002)
Targeted drug delivery by thermally responsive polymers
A Chilkoti et al.
ADVANCED DRUG DELIVERY REVIEWS (2002)
The druggable genome
AL Hopkins et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Reducing capsular thickness and enhancing angiogenesis around implant drug release systems
BD Ratner
JOURNAL OF CONTROLLED RELEASE (2002)
Recent metallic materials for biomedical applications
M Niinomi
METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE (2002)
Pharmacokinetics of the carmustine implant
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CLINICAL PHARMACOKINETICS (2002)
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CLINICAL PHARMACOKINETICS (2002)
Toll-like receptors and innate immunity
R Medzhitov
NATURE REVIEWS IMMUNOLOGY (2001)
Design and synthesis of stimuli-responsive conjugated polymers having azobenzene units in the main chain
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MACROMOLECULES (2001)
'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG):: influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption
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COLLOIDS AND SURFACES B-BIOINTERFACES (2000)
Glucose-sensitivity of glucose oxidase-containing cationic copolymer hydrogels having poly(ethylene glycol) grafts
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JOURNAL OF CONTROLLED RELEASE (2000)
Preparation and dynamic response of cationic copolymer hydrogels containing glucose oxidase
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POLYMER (2000)
Biomaterials in drug delivery and tissue engineering: One laboratory's experience
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ACCOUNTS OF CHEMICAL RESEARCH (2000)
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