期刊
ACTA PSYCHIATRICA SCANDINAVICA
卷 138, 期 1, 页码 55-61出版社
WILEY
DOI: 10.1111/acps.12897
关键词
suicide; depression; neuroendocrinology
类别
资金
- Lightfighter Trust Foundation
Objective: The goal of this study was to determine whether combat veterans who have made a suicide attempt postdeployment can be distinguished from combat veterans who have never made a suicide attempt based on differences in psychological and biological variables. Methods: Demographic and clinical parameters of suicide attempters and non-attempters were assessed. Blood samples were assayed for dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS). Results: Suicide attempters had higher Scale for Suicidal Ideation and Montgomery-angstrom sberg Depression Rating Scale (MADRS)suicidal thoughts item scores in comparison with non-attempters. There was a trend toward higher MADRS scores in the suicide attempter group compared with non-attempters. Suicide attempters had significantly lower levels of DHEA and DHEAS compared with non-attempters. Scale for Suicidal Ideation scores in all study participants combined negatively correlate with DHEA and DHEAS levels. DHEAS levels negatively correlate with Scale for Suicidal Ideation scores in suicide non-attempters but not in suicide attempters. DHEA/DHEAS ratios positively correlate with total adolescence aggression scores, total adulthood aggression scores, and total aggression scale scores in suicide attempters but not in suicide non-attempters. Conclusion: There are psychobiological differences between combat veterans with or without a history of suicidal behaviour.
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