期刊
ACS APPLIED MATERIALS & INTERFACES
卷 10, 期 21, 页码 17714-17721出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsami.8b04433
关键词
clear overlay appliances; polysaccharide; layer by layer assembly; nanofilm; antibacterial coating; durability
资金
- grant of the Korea Health Technology R&D Project through Korea Health Industry Development Institute (KHIDI)
- Ministry of Health & Welfare, Republic of Korea [HI14C3266]
- Basic Science Research Program through National Research Foundation of Korea (NRF) - Ministry of Science and ICT [2014R1A1A1038263, NRF-2017R1E1A1A01074343]
Clear overlay appliances (COAs) are widely used in orthodontic fields because they offer many advantages, such as cost-effectiveness, good formability, and good optical characteristics. However, it is necessary to frequently replace COAs because the thermoplastic polymers that are used to fabricate COAs have poor abrasion resistance and have a tendency to induce bacterial accumulation. Here, we have developed polysaccharide-based antibacterial multilayer films with enhanced durability, intended for COA applications. First, multilayer films composed of carboxymethylcellulose (CMC) and chitosan (CHI) were fabricated on polyethylene terephthalate glycol modified (PETG), which was preferred material for COA fabrication, via a layer by-layer (LbL) technique. Next, chemical cross-linking was introduced within the LbL-assembled multilayer films. The LbL-assembled CMC/CHI film, which was made porous and rough by the cross-linking, formed a superhydrophilic surface to prevent the adhesion of bacteria and exhibited a bacterial reduction ratio of similar to 75%. Furthermore, the cross-linking of the multilayer film coated on the PETG also improved the chemical resistance and mechanical stability of the PETG under simulated intraoral conditions with artificial saliva, by increasing the bond strength between the polysaccharide chains. We attempted to accumulate datasets using our experimental design and to develop sophisticated methods to assess nanoscale changes through large-scale measurements.
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