期刊
EXERCISE AND SPORT SCIENCES REVIEWS
卷 43, 期 3, 页码 117-124出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/JES.0000000000000044
关键词
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资金
- Academy of Finland
- Finnish Foundation for Cardiovascular Research
- Finnish Diabetes Research Foundation
- Ministry of Education and Culture, State of Finland
- Japan Society for the Promotion of Science [KAKENHI-18207019, 20650103, 21370111, 22370091, 22650151, 24650401, 24247046, 26560362]
- National Institutes of Health [HL-50306, HL-108328]
- American Heart Association, Heartland Affiliate
- Grants-in-Aid for Scientific Research [22650151, 20650103, 21370111, 26560362, 24650401] Funding Source: KAKEN
- Novo Nordisk Fonden [NNF13OC0004987] Funding Source: researchfish
The systematic increase in VO2 uptake and O-2 extraction with increasing work rates conceals a substantial heterogeneity of O-2 delivery (QO(2))-to- VO2 matching across and within muscles and other organs. We hypothesize that whether increased/decreased QO(2)/VO2 heterogeneity can be judged as good or bad, for example, after exercise training or in aged individuals or with disease (heart failure, diabetes) depends on the resultant effects on O-2 transport and contractile performance.
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