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BIOMATERIALS (2012)
Neuroprotective effects of osthole pretreatment against traumatic brain injury in rats
Yalong He et al.
BRAIN RESEARCH (2012)
Mechanism of osthole inhibition of vascular Cav1.2 current
Fabio Fusi et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Main constituents from the seeds of Vietnamese Cnidium monnieri and cytotoxic activity
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NATURAL PRODUCT RESEARCH (2012)
Growth Inhibition and Apoptosis Induced by Osthole, A Natural Coumarin, in Hepatocellular Carcinoma
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PLOS ONE (2012)
Involvement of the cGMP pathway in the osthole-facilitated glutamate release in rat hippocampal nerve endings
Tzu Yu Lin et al.
SYNAPSE (2012)
Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-κB-mediated matrix metalloproteinase-9 expression
Shang-Jyh Kao et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)
Isolation and identification of metabolites of osthole in rats
X. Lv et al.
XENOBIOTICA (2012)
Osthole, a natural coumarin, improves neurobehavioral functions and reduces infarct volume and matrix metalloproteinase-9 activity after transient focal cerebral ischemia in rats
Xuexuan Mao et al.
BRAIN RESEARCH (2011)
Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors
Wei-Jan Huang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)
Osthol ameliorates fat milk-induced fatty liver in mice by regulation of hepatic sterol regulatory element-binding protein-1c/2-mediated target gene expression
Rao Du et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Insights into structure-activity relationship of GABAA receptor modulating coumarins and furanocoumarins
Judith Singhuber et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay
Jacques Pantel et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes
Janine Zaugg et al.
FITOTERAPIA (2011)
Osthole Suppresses Hepatocyte Growth Factor (HGF)-Induced Epithelial-Mesenchymal Transition via Repression of the c-Met/Akt/mTOR Pathway in Human Breast Cancer Cells
Chao-Ming Hung et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2011)
Osthole Enhances Glucose Uptake through Activation of AMP-Activated Protein Kinase in Skeletal Muscle Cells
Wei-Hwa Lee et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2011)
Application of hollow fiber liquid phase microextraction coupled with high-performance liquid chromatography for the study of the osthole pharmacokinetics in cerebral ischemia hypoperfusion rat plasma
Jun Zhou et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2011)
Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway
Xiaoman Xu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2011)
Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells
Eunjin Shin et al.
JOURNAL OF NATURAL MEDICINES (2011)
NEUROPROTECTIVE EFFECT OF OSTHOLE AGAINST OXYGEN AND GLUCOSE DEPRIVATION IN RAT CORTICAL NEURONS: INVOLVEMENT OF MITOGEN-ACTIVATED PROTEIN KINASE PATHWAY
T. Chen et al.
NEUROSCIENCE (2011)
Osthole Improves Alcohol-Induced Fatty Liver in Mice by Reduction of Hepatic Oxidative Stress
Jianjun Zhang et al.
PHYTOTHERAPY RESEARCH (2011)
Osthole Ameliorates Insulin Resistance by Increment of Adiponectin Release in High-Fat and High-Sucrose-Induced Fatty Liver Rats
Zhigang Qi et al.
PLANTA MEDICA (2011)
Anthelmintic activity of the crude extracts, fractions, and osthole from Radix angelicae pubescentis against Dactylogyrus intermedius in goldfish (Carassius auratus) in vivo
Kai-yu Wang et al.
PARASITOLOGY RESEARCH (2011)
Osthol, a Coumarin Isolated from Common Cnidium Fruit, Enhances the Differentiation and Maturation of Osteoblasts in vitro
Lei-Guo Ming et al.
PHARMACOLOGY (2011)
Reduction of isoprenaline-induced myocardial TGF-β1 expression and fibrosis in osthole-treated mice
Rong Chen et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2011)
Prenylcoumarin with Rev-export inhibitory activity from Cnidii Monnieris Fructus
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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Effects of Osthole on Migration and Invasion in Breast Cancer Cells
Dapeng Yang et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2010)
Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats
Xiaodong Chao et al.
BRAIN RESEARCH (2010)
Synthesis of N-Hydroxycinnamides Capped with a Naturally Occurring Moiety as Inhibitors of Histone Deacetylase
Wei-Jan Huang et al.
CHEMMEDCHEM (2010)
Attenuation of experimental autoimmune encephalomyelitis in C57 BL/6 mice by osthole, a natural coumarin
Xiaohong Chen et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
Osthole improves chronic cerebral hypoperfusion induced cognitive deficits and neuronal damage in hippocampus
Hai-Jie Ji et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
5-Lipoxygenase inhibitors: a review of recent developments and patents
Carlo Pergola et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2010)
Osthole Regulates Inflammatory Mediator Expression through Modulating NF-κB, Mitogen-Activated Protein Kinases, Protein Kinase C, and Reactive Oxygen Species
Pei-Chun Liao et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)
Osthole Suppresses Fatty Acid Synthase Expression in HER2-Overexpressing Breast Cancer Cells through Modulating Akt/mTOR Pathway
Victor Chia-Hsiang Lin et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)
Antifungal activity of the osthol derivative JS-B against Phytophthora capsici
Chun-Mei Wang et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2010)
Osthole Stimulates Osteoblast Differentiation and Bone Formation by Activation of beta-Catenin-BMP Signaling
De-Zhi Tang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Neuroprotective effect of osthole on MPP+-induced cytotoxicity in PC12 cells via inhibition of mitochondrial dysfunction and ROS production
Wen-Bo Liu et al.
NEUROCHEMISTRY INTERNATIONAL (2010)
Osthol regulates hepatic PPARα-mediated lipogenic gene expression in alcoholic fatty liver murine
Fan Sun et al.
PHYTOMEDICINE (2010)
Osthol is a Use-Dependent Blocker of Voltage-Gated Na+ Channels in Mouse Neuroblastoma N2A Cells
Yuk-Man Leung et al.
PLANTA MEDICA (2010)
Osthole or Imperatorin-Mediated Facilitation of Glutamate Release Is Associated With a Synaptic Vesicle Mobilization in Rat Hippocampal Glutamatergic Nerve Endings
Tzu-Yu Lin et al.
SYNAPSE (2010)
The Effect of the Major Components of Fructus Cnidii on Osteoblasts In Vitro
Wenping Zhang et al.
JOURNAL OF ACUPUNCTURE AND MERIDIAN STUDIES (2010)
Osthole, a potential antidiabetic agent, alleviates hyperglycemia in db/db mice
Hong-Jen Liang et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2009)
Inhibitory effect of osthole on alcohol-induced fatty liver in mice
F. Sun et al.
DIGESTIVE AND LIVER DISEASE (2009)
Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: A comparative study
Jarogniew J. Luszczki et al.
EPILEPSY RESEARCH (2009)
Osthole suppresses seizures in the mouse maximal electroshock seizure model
Jarogniew J. Luszczki et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Efficacy of osthol, a potent coumarin compound, in controlling powdery mildew caused by Sphaerotheca fuliginea
Chun-Mei Wang et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2009)
Effects of osthole on apoptosis and TGF-beta(1) of hypertrophic scar fibroblasts
Xiao-Hua Hou et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2009)
Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7
Tomonori Nakamura et al.
JOURNAL OF NATURAL MEDICINES (2009)
Determination of osthol and its metabolites in a phase I reaction system and the Caco-2 cell model by HPLC-UV and LC-MS/MS
Zhenting Yuan et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2009)
Determination of osthole in rat plasma by high-performance liquid chromatograph using cloud-point extraction
Jun Zhou et al.
ANALYTICA CHIMICA ACTA (2008)
Identification of natural coumarin compounds that rescue defective ΔF508-CFTR chloride channel gating
Li-Na Xu et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2008)
Fusarium graminearum growth inhibition due to glucose starvation caused by osthol
Zhiqi Shi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2008)
Petroleum ether extract of Cnidium monnieri ameliorated scopolamine-induced amnesia through adrenal gland-mediated mechanism in male rats
Chi-Rei Wu et al.
JOURNAL OF ETHNOPHARMACOLOGY (2008)
Osthole and imperatorin, the active constituents of Cnidium monnieri (L.) Cusson, facilitate glutamate release from rat hippocampal nerve terminals
Su-Jane Wang et al.
NEUROCHEMISTRY INTERNATIONAL (2008)
Effect of the Chinese Herb Extract Osthol on IL-4-induced Eotaxin Expression in BEAS-2B Cells
Pu-Rong Chiu et al.
Pediatrics and Neonatology (2008)
Osthol and isopimpinellin from Fructus cnidii for the control of Dactylogyrus intermedius in Carassius auratus
Gaoxue Wang et al.
VETERINARY PARASITOLOGY (2008)
Constituents, biological activities and quality control parameters of the crude extract and essential oil from Arracacia tolucensis var. multifida
Mario Figueroa et al.
JOURNAL OF ETHNOPHARMACOLOGY (2007)
Osthole improves fat milk-induced fatty liver in rats: Modulation of hepatic PPAR-alpha/gamma-mediated lipogenic gene expression
Yan Zhang et al.
PLANTA MEDICA (2007)
Effects of osthol on blood pressure and lipid metabolism in stroke-prone spontaneously hypertensive rats
Hiroshi Ogawa et al.
JOURNAL OF ETHNOPHARMACOLOGY (2007)
Therapeutic effect of osthole on hyperlipidemic fatty liver in rats
Yan Zhang et al.
ACTA PHARMACOLOGICA SINICA (2007)
Antitumor effects of osthol from Cnidium monnieri:: An in vitro and in vivo study
Szu-Yuan Chou et al.
PHYTOTHERAPY RESEARCH (2007)
Antibacterial and anticoagulant activities of coumarins isolated from the flowers of Magydaris tomentosa
Sergio Rosselli et al.
PLANTA MEDICA (2007)
Coumarins from Cnidium monnieri and their antiosteoporotic activity
Qiaoyan Zhang et al.
PLANTA MEDICA (2007)
Synthetic derivatives of osthole for the prevention of hepatitis
Toshihiro Okamoto et al.
MEDICINAL CHEMISTRY (2007)
Antiproliferative effects of isopentenylated coumarins isolated from Phellolophium madagascariense Baker
C. Riviere et al.
NATURAL PRODUCT RESEARCH (2006)
Experimental study of osthole on treatment of hyperlipidemic and alcoholic fatty liver in animals
Fang Song et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2006)
Cyclic nucleotide regulation of store-operated Ca2+ influx in airway smooth muscle
B Ay et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)
HPLC determination and pharmacokinetics of osthole in rat plasma after oral administration of fructus cnidii extract
YB Li et al.
JOURNAL OF CHROMATOGRAPHIC SCIENCE (2005)
Osthole improves aspects of spatial performance in ovariectomized rats
MT Hsieh et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2004)
Osthole prevents anti-Fas antibody-induced hepatitis in mice by affecting the caspase-3-mediated apoptotic pathway
T Okamoto et al.
BIOCHEMICAL PHARMACOLOGY (2003)
Prostaglandins inhibit 5-lipoxygenase-activating protein expression and leukotriene B-4 production from dendritic cells via an IL-10-dependent mechanism
H Harizi et al.
JOURNAL OF IMMUNOLOGY (2003)
Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils
N Flamand et al.
MOLECULAR PHARMACOLOGY (2002)
Anti-allergic effects of Cnidii Monnieri Fructus (Dried fruits of Cnidium monnieri) and its major component, osthol
H Matsuda et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2002)
Effects of osthole on postmenopausal osteoporosis using ovariectomized rats; Comparison to the effects of estradiol
XX Li et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2002)
Inhibitory effect of the plant-extract osthole on L-type calcium current in NG108-15 neuronal cells
SN Wu et al.
BIOCHEMICAL PHARMACOLOGY (2002)
The coumarin osthol attenuates the binding of thyrotropin-releasing hormone in rat pituitary GH4C1 tells
T Ojala et al.
PLANTA MEDICA (2001)
Vasorelaxing effect of coumarins from Cnidium monnieri on rabbit corpus cavernosum
WF Chiou et al.
PLANTA MEDICA (2001)
Inhibition of concanavalin A-induced mice hepatitis by coumarin derivatives
T Okamoto et al.
JAPANESE JOURNAL OF PHARMACOLOGY (2001)
Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C
TJ Kamp et al.
CIRCULATION RESEARCH (2000)
Effect of the plant-extract osthole on the relaxation of rabbit corpus cavernosum tissue in vitro
J Chen et al.
JOURNAL OF UROLOGY (2000)