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注意：仅列出部分参考文献，下载原文获取全部文献信息。Rhein Inhibits the Expression of Vascular Cell Adhesion Molecule 1 in Human Umbilical Vein Endothelial Cells with or without Lipopolysaccharide Stimulation
Gang Hu et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2013)
Rhein Protects Pancreatic β-Cells From Dynamin-Related Protein-1-Mediated Mitochondrial Fission and Cell Apoptosis Under Hyperglycemia
Jing Liu et al.
DIABETES (2013)
Protection of rhein on IgA nephropathy mediated by inhibition of fibronectin expression in rats
Peng Sheng-Nan et al.
INDIAN JOURNAL OF PHARMACOLOGY (2013)
Chronic Allograft Nephropathy in Rats Is Improved by the Intervention of Rhein
J. Su et al.
TRANSPLANTATION PROCEEDINGS (2013)
Effects of rhein on intestinal epithelial tight junction in IgA nephropathy
Sheng-Nan Peng et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2013)
Evaluation of natural anthracene-derived compounds as antimitotic agents
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DRUG DISCOVERIES AND THERAPEUTICS (2013)
Rhein Inhibits Integrin-Linked Kinase Expression and Regulates Matrix Metalloproteinase-9/Tissue Inhibitor of Metalloproteinase-1 Ratio in High Glucose-Induced Epithelial-Mesenchymal Transition of Renal Tubular Cell
Linlin Peng et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2012)
ER Stress, P66shc, and P-Akt/Akt Mediate Adjuvant-Induced Inflammation, Which Is Blunted by Argirein, a Supermolecule and Rhein in Rats
Xiao-Dong Cong et al.
INFLAMMATION (2012)
Rhein Protects against Obesity and Related Metabolic Disorders through Liver X Receptor-Mediated Uncoupling Protein 1 Upregulation in Brown Adipose Tissue
Xiaoyan Sheng et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2012)
Improvement of glucose tolerance by rhein with restored early-phase insulin secretion in db/db mice
H. Du et al.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2012)
The hydroalcoholic extract of Cassia alata (Linn.) leaves and its major compound rhein exhibits antiallergic activity via mast cell stabilization and lipoxygenase inhibition
Baljinder Singh et al.
JOURNAL OF ETHNOPHARMACOLOGY (2012)
Protective effect of rhein against oxidative stress-related endothelial cell injury
Xian-Feng Zhong et al.
MOLECULAR MEDICINE REPORTS (2012)
Rhein ameliorates fatty liver disease through negative energy balance, hepatic lipogenic regulation, and immunomodulation in diet-induced obese mice
Xiaoyan Sheng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
Preventive Effects and Mechanisms of Rhein on Renal Interstitial Fibrosis in Obstructive Nephropathy
Dongyuan He et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)
Rhein inhibits angiogenesis and the viability of hormone-dependent and -independent cancer cells under normoxic or hypoxic conditions in vitro
Vivian E. Fernand et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2011)
Rhein protects against acetaminophen-induced hepatic and renal toxicity
Yan-Ling Zhao et al.
FOOD AND CHEMICAL TOXICOLOGY (2011)
Rhein, an inhibitor of adipocyte differentiation and adipogenesis
Qian Liu et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2011)
Rhein: A potential biological therapeutic drug for intervertebral disc degeneration
Hao Li et al.
MEDICAL HYPOTHESES (2011)
Anti-angiogenic effect and mechanism of rhein from Rhizoma Rhei
Zhi-Heng He et al.
PHYTOMEDICINE (2011)
Anti-proliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells
Gabriella Aviello et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)
Rhein Improves Renal Lesion and Ameliorates Dyslipidemia in db/db Mice with Diabetic Nephropathy
Qing Gao et al.
PLANTA MEDICA (2010)
Emodin and rhein inhibit LIGHT-induced monocytes migration by blocking of ROS production
Sook-Kyoung Heo et al.
VASCULAR PHARMACOLOGY (2010)
Targeting CpG DNA to screen and isolate anti-sepsis fraction and monomers from traditional Chinese herbs using affinity biosensor technology
Xin Liu et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2009)
Rhein Inhibits TNF-alpha-Induced Human Aortic Smooth Muscle Cell Proliferation via Mitochondrial-Dependent Apoptosis
Sook-Kyoung Heo et al.
JOURNAL OF VASCULAR RESEARCH (2009)
Rhein inhibits invasion and migration of human nasopharyngeal carcinoma cells in vitro by down-regulation of matrix metalloproteinases-9 and vascular endothelial growth factor
Meng-Liang Lin et al.
ORAL ONCOLOGY (2009)
Inhibition of Cytochrome P450 Enzymes by Rhein in Rat Liver Microsomes
Jing-cheng Tang et al.
PHYTOTHERAPY RESEARCH (2009)
Rhein, the metabolite of diacerhein, reduces the proliferation of osteoarthritic chondrocytes and synoviocytes without inducing apoptosis
F. Legendre et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2009)
Rhein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma BEL-7402 cells
Ping Shi et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2008)
Anti-proliferative effects of estrogen receptor-modulating compounds isolated from Rheum palmatum
Se Chan Kang et al.
ARCHIVES OF PHARMACAL RESEARCH (2008)
Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of rhein in human plasma: application to a pharmacokinetic study
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BIOMEDICAL CHROMATOGRAPHY (2008)
Global transcriptional response of Staphylococcus aureus to Rhein, a Natural Plant Product
Lu Yu et al.
JOURNAL OF BIOTECHNOLOGY (2008)
Modulatory effect of rhein on IL-1 alpha-induced responses in human chondrocytes: A comparative study between antibody microarrays and specific ELISAs
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BIORHEOLOGY (2008)
Anthraquinone-2,6-disulfonic acid as a disease-modifying osteoarthritis drug
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CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2007)
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
Thomas A. Wynn
JOURNAL OF CLINICAL INVESTIGATION (2007)
Insulin sensitizing and α-glucoamylase inhibitory action of sennosides, rheins and rhaponticin in Rhei Rhizoma
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LIFE SCIENCES (2006)
Rhein inhibits the growth and induces the apoptosis of Hep G2 cells
PL Kuo et al.
PLANTA MEDICA (2004)
Rhein induces apoptosis in HL-60 cells via reactive oxygen species-independent mitochondrial death pathway
SG Lin et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Rhein inhibits interleukin-1β-induced activation of MEK/ERK pathway and DNA binding of NF-κB and AP-1 in chondrocytes cultured in hypoxia:: A potential mechanism for its disease-modifying effect in osteoarthritis
G Martin et al.
INFLAMMATION (2003)
Effects of rhein on human articular chondrocytes in alginate beads
C Sanchez et al.
BIOCHEMICAL PHARMACOLOGY (2003)
Diacerhein and rhein prevent interleukin-1β-induced nuclear factor-κB activation by inhibiting the degradation of inhibitor κB-α
AF Mendes et al.
PHARMACOLOGY & TOXICOLOGY (2002)
Reactive nitrogen species modulate the effects of rhein, an active component of senna laxatives, on human epithelium in vitro
F Raimondi et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2002)
Rhein, an active metabolite of diacerein, down-regulates the production of pro-matrix metalloproteinases-1,-3,-9 and-13 and up-regulates the production of tissue inhibitor of metalloproteinase-1 in cultured rabbit articular chondrocytes
T Tamura et al.
OSTEOARTHRITIS AND CARTILAGE (2001)
Inhibition of the nitrosothiol production of cultured osteoarthritic chondrocytes by rhein, cortisol and diclofenac
D Borderie et al.
OSTEOARTHRITIS AND CARTILAGE (2001)
Rhein, an active metabolite of diacerein, suppresses the interleukin-1 alpha-induced proteoglycan degradation in cultured rabbit articular chondrocytes
T Tamura et al.
JAPANESE JOURNAL OF PHARMACOLOGY (2001)
Effects of diacerein on indomethacin-induced gastric ulceration
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PHARMACOLOGY (2001)
Diacerhein and rhein reduce the ICE-induced IL-1β and IL-18 activation in human osteoarthritic cartilage
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OSTEOARTHRITIS AND CARTILAGE (2000)
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