期刊
WORLD JOURNAL OF DIABETES
卷 7, 期 17, 页码 342-353出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.4239/wjd.v7.i17.342
关键词
Diabetes mellitus; Neuropathy; Diabetic neuropathy; Median entrapment neuropathy at the wrist; Ulnar entrapment neuropathy at the elbow; Ulnar entrapment neuropathy at the wrist; Carpal tunnel syndrome; Electrodiagnosis; Tarsal tunnel syndrome
Neuropathy is a common complication of diabetes mellitus (DM) with a wide clinical spectrum that encompasses generalized to focal and multifocal forms. Entrapment neuropathies (EN), which are focal forms, are so frequent at any stage of the diabetic disease, that they may be considered a neurophysiological hallmark of peripheral nerve involvement in DM. Indeed, EN may be the earliest neurophysiological abnormalities in DM, particularly in the upper limbs, even in the absence of a generalized polyneuropathy, or it may be superimposed on a generalized diabetic neuropathy. This remarkable frequency of EN in diabetes is underlain by a peculiar pathophysiological background. Due to the metabolic alterations consequent to abnormal glucose metabolism, the peripheral nerves show both functional impairment and structural changes, even in the preclinical stage, making them more prone to entrapment in anatomically constrained channels. This review discusses the most common and relevant EN encountered in diabetic patient in their epidemiological, pathophysiological and diagnostic features.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据