4.3 Article

Refractory Pseudomonas Bacteremia in a 2-Year-Old Sterilized by Bacteriophage Therapy

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出版社

OXFORD UNIV PRESS
DOI: 10.1093/jpids/pix056

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bacteremia; bacteriophage; multidrug resistance; Pseudomonas aeruginosa; sepsis

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  1. Biological Defense Research Directorate of the Naval Medical Research Center

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Here, we report a complex case that involved a pediatric patient who experienced recalcitrant multidrug-resistant Pseudomonas aeruginosa infection complicated by bacteremia/sepsis; our antibacterial options were limited because of resistance, allergies, and suboptimal source control. A cocktail of 2 bacteriophages targeting the infectious organism introduced on 2 separate occasions sterilized the bacteremia.

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