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Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death
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C9orf72 is required for proper macrophage and microglial function in mice
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Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling
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A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy
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The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway
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Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
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TMEM106B, a frontotemporal lobar dementia (FTLD) modifier, associates with FTD-3-linked CHMP2B, a complex of ESCRT-III
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