4.6 Article

Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling

Joseph Amick et al.

MOLECULAR BIOLOGY OF THE CELL (2016)

Article Multidisciplinary Sciences

C9orf72 is required for proper macrophage and microglial function in mice

J. G. O'Rourke et al.

SCIENCE (2016)

Article Genetics & Heredity

Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling

Janet Ugolino et al.

PLOS GENETICS (2016)

Article Multidisciplinary Sciences

A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy

Mei Yang et al.

SCIENCE ADVANCES (2016)

Article Neurosciences

The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway

Peter M. Sullivan et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2016)

Article Cell Biology

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

Xiaolai Zhou et al.

JOURNAL OF CELL BIOLOGY (2015)

Editorial Material Clinical Neurology

TMEM106B: a strong FTLD disease modifier

Yuetiva Deming et al.

ACTA NEUROPATHOLOGICA (2014)

Article Clinical Neurology

TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia

Marka van Blitterswijk et al.

ACTA NEUROPATHOLOGICA (2014)

Article Biochemistry & Molecular Biology

The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes

Benjamin M. Schwenk et al.

EMBO JOURNAL (2014)

Article Neurosciences

Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B

Massimiliano Stagi et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2014)

Review Clinical Neurology

Neuronal Ceroid Lipofuscinosis: Impact of Recent Genetic Advances and Expansion of the Clinicopathologic Spectrum

Susan L. Cotman et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2013)

Article Biochemistry & Molecular Biology

The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function

Owen A. Brady et al.

HUMAN MOLECULAR GENETICS (2013)

Article Genetics & Heredity

Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage

Katherine R. Smith et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2012)

Editorial Material Clinical Neurology

TMEM106B RISK VARIANT IS IMPLICATED IN THE PATHOLOGIC PRESENTATION OF ALZHEIMER DISEASE

Nicola J. Rutherford et al.

NEUROLOGY (2012)

Article Biochemistry & Molecular Biology

Transcriptional gene network inference from a massive dataset elucidates transcriptome organization and gene function

Vincenzo Belcastro et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Genetics & Heredity

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP43 inclusions

Vivianna M. Van Deerlin et al.

NATURE GENETICS (2010)

Article Endocrinology & Metabolism

Lysosomal accumulation of SCMAS (subunit c of mitochondrial ATP synthase) in neurons of the mouse model of mucopolysaccharidosis IIIB

Sergey Ryazantsev et al.

MOLECULAR GENETICS AND METABOLISM (2007)

Article Biochemistry & Molecular Biology

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Biochemistry & Molecular Biology

Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

Jennifer Gass et al.

HUMAN MOLECULAR GENETICS (2006)

Article Multidisciplinary Sciences

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Manuela Neumann et al.

SCIENCE (2006)

Review Clinical Neurology

Frontotemporal dementia

D Neary et al.

LANCET NEUROLOGY (2005)

Article Clinical Neurology

The prevalence of frontotemporal dementia

E Ratnavalli et al.

NEUROLOGY (2002)