期刊
MOLECULAR IMAGING
卷 16, 期 -, 页码 -出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1536012117718459
关键词
immunotherapy; PET; SPECT; optical imaging; atezolizumab; peptide; PD-1
资金
- Allegheny Health Network-Johns Hopkins Cancer Research Fund
- NIHP30 CA006973
- [NIHR01CA16631]
Immunotherapy holds great promise in cancer treatment. The challenges in advancing immunotherapies lie in patient stratification and monitoring therapy. Noninvasive detection of immune checkpoint ligand PD-L1 can serve as an important biomarker for guidance and monitoring of immunotherapy. Here in, we provide an overview of our efforts to develop clinically translatable PD-L1-specific imaging agents for quantitative and real-time assessment of PD-L1 expression in tumor microenvironment.
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