期刊
PHYSICAL REVIEW E
卷 94, 期 4, 页码 -出版社
AMER PHYSICAL SOC
DOI: 10.1103/PhysRevE.94.042410
关键词
-
资金
- NSF [PHY13-16748]
- Division Of Physics
- Direct For Mathematical & Physical Scien [1316748] Funding Source: National Science Foundation
We propose a new topological characterization of ribonucleic acid (RNA) secondary structures with pseudoknots based on two topological invariants. Starting from the classic arc representation of RNA secondary structures, we consider a model that couples both (i) the topological genus of the graph and (ii) the number of crossing arcs of the corresponding primitive graph. We add a term proportional to these topological invariants to the standard free energy of the RNA molecule, thus obtaining a novel free-energy parametrization that takes into account the abundance of topologies of RNA pseudoknots observed in RNA databases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据