4.2 Article

A lucrative chemical processing of bamboo leaf biomass to synthesize biocompatible amorphous silica nanoparticles of biomedical importance

期刊

APPLIED NANOSCIENCE
卷 7, 期 5, 页码 145-153

出版社

SPRINGER HEIDELBERG
DOI: 10.1007/s13204-017-0557-z

关键词

Bamboo leaf biomass; Mass production; Silica nanoparticles; Biocompatibility; Drug delivery

资金

  1. University Grants Commission (UGC), New Delhi [F.15-1/2015-17/PDFWM-2015-17-TAM-36274]

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Synthesis of silica nanoparticles from natural resources/waste via cost effective route is presently one of the anticipating strategies for extensive applications. This study reports the low-cost indigenous production of silica nanoparticles from the leftover of bamboo (leaf biomass) through thermal combustion and alkaline extraction, and examination of physico-chemical properties and yield percentage using comprehensive characterization tools. The outcome of primed silica powder exhibits amorphous particles (average size: 25 nm) with high surface area (428 m(2) g(-1)) and spherical morphology. Despite the yield percentage of silica nanoparticles from bamboo leave ash is 50.2%, which is less than rice husk ask resources (62.1%), the bamboo waste is only an inexpensive resource yielding high purity (99%). Synthesis of silica nanoparticles from natural resources/waste with the help of lucrative route is at present times one of the anticipating strategies for extensive applications. In vitro study on animal cell lines (MG63) shows non-toxic nature of silica nanoparticles up to 125 mu g mL(-1). Hence, this study highlights the feasibility for the mass production of silica nanoparticles from bamboo leave waste rather using chemical precursor of silica for drug delivery and other medical applications.

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