期刊
PROBIOTICS AND ANTIMICROBIAL PROTEINS
卷 10, 期 3, 页码 456-465出版社
SPRINGER
DOI: 10.1007/s12602-017-9357-8
关键词
Lactic acid bacteria; Enterococcus faecalis; Beneficial traits; Bacteriocin; In silico analysis
资金
- French and Iraqi government joint agreement (Campus France)
- La region des Hauts de France through Alibiotech programme (2015-2020)
This study aimed at comparing the genome of Enterococcus faecalis B3A-B3B, a bacteriocinogenic strain recently isolated from a healthy Iraqi infant to those of Enterococci of clinical and beneficial grades. The putative genes gelE, cpd, efaAfm, ccf, agg, and cob coding for virulence factors were detected in B3A-B3B strain, which meanwhile resulted to be non-cytotoxic, non-hemolytic, devoid of inflammatory effects, and sensitive to most of the antibiotics tested except for clindamycin and trimethoprim, which resistance is usually ascribed to intrinsic nature. B3A-B3B strain was remarkable for its hydrophobicity, auto-aggregation, adhesion to human Caco-2 cells, and survival in simulated gastrointestinal conditions, and cholesterol assimilation fulfilling therefore key beneficial attributes.
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