期刊
ORGANIC CHEMISTRY FRONTIERS
卷 4, 期 11, 页码 2124-2127出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7qo00549k
关键词
-
资金
- JSPS (KAKENHI) [16K18849]
- Hoyu Science Foundation
- Grants-in-Aid for Scientific Research [16K18849] Funding Source: KAKEN
We have developed a self-relay copper(I)-catalyzed Ullmann N-arylation/2-amidation cascade to form functionalized indolo[1,2-a]quinazolinones in one-pot from easily available indoles with 2-bromobenzamides. This novel transformation features a tandem process of Ullmann-type coupling, activation of indolenine, and 2-amidation in the presence of a single copper catalyst. In addition, among the substituents of indoles at the C3 position, methyl carboxylate could act as an activating group in this Ullmann N-arylation/2-amidation cascade.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据