期刊
JOURNAL OF ORAL MICROBIOLOGY
卷 9, 期 -, 页码 -出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/20002297.2017.1300366
关键词
Porphyromonas gingivalis; biofilms; new antibacterial agents
类别
资金
- Industrial Research Fund of KU Leuven [IOF/KP/11/007]
- European Commission's Seventh Framework Program [COATIM] [278425]
- Research Foundation - Flanders FWO [G0B2515N, G.0471.12N, G.0413.10]
- Interuniversity Attraction Poles Program
- Belgian Science Policy Office [P7/28]
In nature, bacteria predominantly reside in structured, surface-attached communities embedded in a self-produced, extracellular matrix. These so-called biofilms play an important role in the development and pathogenesis of many infections, as they are difficult to eradicate due to their resistance to antimicrobials and host defense mechanisms. This review focusses on the biofilm-forming periodontal bacterium Porphyromonas gingivalis. Current knowledge on the virulence mechanisms underlying P. gingivalis biofilm formation is presented. In addition, oral infectious diseases in which P. gingivalis plays a key role are described, and an overview of conventional and new therapies for combating P. gingivalis biofilms is given. More insight into this intriguing pathogen might direct the development of better strategies to combat oral infections.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据