期刊
FRONTIERS IN IMMUNOLOGY
卷 8, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2017.00014
关键词
protozoan infections; IFN-I; Leishmania; Toxoplasma; Plasmodium; Trypanosoma
类别
资金
- Canadian Institutes of Health Research [MOP 123293]
- Natural Science and Engineering Research Council of Canada
- Fondation Armand-Frappier
For many years, the role of interferon (IFN)-I has been characterized primarily in the context of viral infections. However, regulatory functions mediated by IFN-I have also been described against bacterial infections and in tumor immunology. Only recently, the interest in understanding the immune functions mediated by IFN-I has dramatically increased in the field of protozoan infections. In this review, we discuss the discrete role of IFN-I in the immune response against major protozoan infections: Plasmodium, Leishmania, Trypanosoma, and Toxoplasma.
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