相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway
Rojo A. Ratsimandresy et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2017)
Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome
Pedro A. Ruiz et al.
GUT (2017)
Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells
M. A. Pallett et al.
MUCOSAL IMMUNOLOGY (2017)
NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and-8
Isabella Rauch et al.
IMMUNITY (2017)
Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells
Shu Zhu et al.
NATURE (2017)
Recent Insights into the Molecular Mechanisms Underlying Pyroptosis and Gasdermin Family Functions
Robin A. Aglietti et al.
TRENDS IN IMMUNOLOGY (2017)
Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation
Adrian J. Blazejewski et al.
CELL REPORTS (2017)
Genetic and epigenetic Determinants in Autoinflammatory Diseases
Damiana Alvarez-Errico et al.
FRONTIERS IN IMMUNOLOGY (2017)
Differential roles of caspase-1 and caspase-11 in infection and inflammation
Si Ming Man et al.
SCIENTIFIC REPORTS (2017)
NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth
Liang Chen et al.
NATURE IMMUNOLOGY (2017)
Programmed cell death and the immune system
Shigekazu Nagata et al.
NATURE REVIEWS IMMUNOLOGY (2017)
Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages
Cornelius Y. Taabazuing et al.
CELL CHEMICAL BIOLOGY (2017)
Noncanonical inflammasomes: Antimicrobial defense that does not play by the rules
Shauna M. Crowley et al.
CELLULAR MICROBIOLOGY (2017)
Mechanisms of NLRP3 inflammasome activation and its role in NSAID-induced enteropathy
A. Higashimori et al.
MUCOSAL IMMUNOLOGY (2016)
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome
Aleksey Chudnovskiy et al.
CELL (2016)
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation
F. Martin-Sanchez et al.
CELL DEATH AND DIFFERENTIATION (2016)
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
Xin Chen et al.
CELL RESEARCH (2016)
Fusobacterium nucleatum infection of gingival epithelial cells leads to NLRP3 inflammasome-dependent secretion of IL-1 and the danger signals ASC and HMGB1
Fiona Q. Bui et al.
CELLULAR MICROBIOLOGY (2016)
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
Lorenzo Sborgi et al.
EMBO JOURNAL (2016)
IL-1β, IL-18, and eicosanoids promote neutrophil recruitment to pore-induced intracellular traps following pyroptosis
Ine Jorgensen et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2016)
Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules
Hae Woong Choi et al.
IMMUNITY (2016)
Human Monocytes Engage an Alternative Inflammasome Pathway
Moritz M. Gaidt et al.
IMMUNITY (2016)
NLRP3 recruitment by NLRC4 during Salmonella infection
Yan Qu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Pore-forming activity and structural autoinhibition of the gasdermin family
Jingjin Ding et al.
NATURE (2016)
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
Xing Liu et al.
NATURE (2016)
Organoids as an in vitro model of human development and disease
Aliya Fatehullah et al.
NATURE CELL BIOLOGY (2016)
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
Robin A. Aglietti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells
Giuseppina Arbore et al.
SCIENCE (2016)
NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation
Ivan Tattoli et al.
CELL REPORTS (2016)
An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection
Anna A. Mueller et al.
PLOS PATHOGENS (2016)
Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling
Maayan Levy et al.
CELL (2015)
Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis
Roni Nowarski et al.
CELL (2015)
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Wan-ting He et al.
CELL RESEARCH (2015)
The NAIP/NLRC4 inflammasomes
Russell E. Vance
CURRENT OPINION IN IMMUNOLOGY (2015)
Non-canonical activation of inflammatory caspases by cytosolic LPS in innate immunity
Jieling Yang et al.
CURRENT OPINION IN IMMUNOLOGY (2015)
Mechanisms of unconventional secretion of IL-1 family cytokines
Mercedes Monteleone et al.
CYTOKINE (2015)
Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury
Sang-Uk Seo et al.
IMMUNITY (2015)
Interleukin-22 Induces Interleukin-18 Expression from Epithelial Cells during Intestinal Infection
Melba Munoz et al.
IMMUNITY (2015)
Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme
Inna S. Afonina et al.
IMMUNITY (2015)
Epithelial NAIPs protect against colonic tumorigenesis
Ramanjaneyulu Allam et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
The NLRP1 Inflammasome Attenuates Colitis and Colitis-Associated Tumorigenesis
Tere M. Williams et al.
JOURNAL OF IMMUNOLOGY (2015)
Epithelial-derived IL-18 regulates Th17 cell differentiation and Foxp3+ Treg cell function in the intestine
O. J. Harrison et al.
MUCOSAL IMMUNOLOGY (2015)
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nobuhiko Kayagaki et al.
NATURE (2015)
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi et al.
NATURE (2015)
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease
Yun-Hee Youm et al.
NATURE MEDICINE (2015)
Inflammasomes of the intestinal epithelium
Mikael E. Sellin et al.
TRENDS IN IMMUNOLOGY (2015)
DAC can restore expression of NALP1 to suppress tumor growth in colon cancer
C. Chen et al.
CELL DEATH & DISEASE (2015)
Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome
Laurence Macia et al.
NATURE COMMUNICATIONS (2015)
The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense
Shuiqing Hu et al.
CELL REPORTS (2015)
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
L. Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2015)
Protective Role for Caspase-11 during Acute Experimental Murine Colitis
Katarzyna Oficjalska et al.
JOURNAL OF IMMUNOLOGY (2015)
NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion
Marta Wlodarska et al.
CELL (2014)
Epithelium-Intrinsic NAIP/NLRC4 Inflammasome Drives Infected Enterocyte Expulsion to Restrict Salmonella Replication in the Intestinal Mucosa
Mikael E. Sellin et al.
CELL HOST & MICROBE (2014)
Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens
Leigh A. Knodler et al.
CELL HOST & MICROBE (2014)
The IL18RAP Region Disease Polymorphism Decreases IL-18RAP/IL-18R1/IL-1R1 Expression and Signaling through Innate Receptor-Initiated Pathways
Matija Hedl et al.
JOURNAL OF IMMUNOLOGY (2014)
Integrin-Mediated First Signal for Inflammasome Activation in Intestinal Epithelial Cells
Josephine Thinwa et al.
JOURNAL OF IMMUNOLOGY (2014)
A Critical Role for Human Caspase-4 in Endotoxin Sensitivity
Yuji Kajiwara et al.
JOURNAL OF IMMUNOLOGY (2014)
NLRC4 expression in intestinal epithelial cells mediates protection against an enteric pathogen
S. Nordlander et al.
MUCOSAL IMMUNOLOGY (2014)
Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen
G. X. Song-Zhao et al.
MUCOSAL IMMUNOLOGY (2014)
Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis
D. Demon et al.
MUCOSAL IMMUNOLOGY (2014)
Inflammatory caspases are innate immune receptors for intracellular LPS
Jianjin Shi et al.
NATURE (2014)
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases
Etienne Meunier et al.
NATURE (2014)
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
Zhenyu Cai et al.
NATURE CELL BIOLOGY (2014)
Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2
Patricia R. Taylor et al.
NATURE IMMUNOLOGY (2014)
Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex
Si Ming Man et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling
Naomi H. Philip et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18
Benyue Zhang et al.
SCIENCE (2014)
Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation
Fraenze Progatzky et al.
NATURE COMMUNICATIONS (2014)
The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge
Kaiwen W. Chen et al.
CELL REPORTS (2014)
Recognition of Bacteria by Inflammasomes
Jakob von Moltke et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
V. Sagulenko et al.
CELL DEATH AND DIFFERENTIATION (2013)
The Shigella OspC3 Effector Inhibits Caspase-4, Antagonizes Inflammatory Cell Death, and Promotes Epithelial Infection
Taira Kobayashi et al.
CELL HOST & MICROBE (2013)
Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection
Youssef Aachoui et al.
CURRENT OPINION IN MICROBIOLOGY (2013)
ASC Controls IFN-γ Levels in an IL-18-Dependent Manner in Caspase-1-Deficient Mice Infected with Francisella novicida
Roberto Pierini et al.
JOURNAL OF IMMUNOLOGY (2013)
Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications
Toshiro Sato et al.
SCIENCE (2013)
Crystal Structure of NLRC4 Reveals Its Autoinhibition Mechanism
Zehan Hu et al.
SCIENCE (2013)
Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
Jon A. Hagar et al.
SCIENCE (2013)
Caspase-11 Protects Against Bacteria That Escape the Vacuole
Youssef Aachoui et al.
SCIENCE (2013)
Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
Nobuhiko Kayagaki et al.
SCIENCE (2013)
Activation and regulation of the inflammasomes
Eicke Latz et al.
NATURE REVIEWS IMMUNOLOGY (2013)
TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria
Vijay A. K. Rathinam et al.
CELL (2012)
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
L. Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2012)
Role of mucus layers in gut infection and inflammation
Gunnar C. Hansson
CURRENT OPINION IN MICROBIOLOGY (2012)
Structure and Functional Characterization of the RNA-Binding Element of the NLRX1 Innate Immune Modulator
Minsun Hong et al.
IMMUNITY (2012)
The NLRP12 Inflammasome Recognizes Yersinia pestis
Gregory I. Vladimer et al.
IMMUNITY (2012)
An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages
Sonal Khare et al.
IMMUNITY (2012)
NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling
Irving C. Allen et al.
IMMUNITY (2012)
Critical Role for MyD88-Mediated Neutrophil Recruitment during Clostridium difficile Colitis
Irene Jarchum et al.
INFECTION AND IMMUNITY (2012)
Commensal and probiotic bacteria influence intestinal barrier function and susceptibility to colitis in Nod1-/-;Nod2-/- Mice
Jane M. M. Natividad et al.
INFLAMMATORY BOWEL DISEASES (2012)
Role of Inflammasomes in Host Defense against Citrobacter rodentium Infection
Zhiping Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Toll or Interleukin-1 Receptor (TIR) Domain-containing Adaptor Inducing Interferon-β (TRIF)-mediated Caspase-11 Protease Production Integrates Toll-like Receptor 4 (TLR4) Protein- and Nlrp3 Inflammasome-mediated Host Defense against Enteropathogens
Prajwal Gurung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells
Margherita Coccia et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice
Carles Ubeda et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
Petr Broz et al.
NATURE (2012)
Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
Jakob von Moltke et al.
NATURE (2012)
Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine
Jeremiah R. McDole et al.
NATURE (2012)
NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense
Luigi Franchi et al.
NATURE IMMUNOLOGY (2012)
Immunization withStaphylococcus aureusiron regulated surface determinant B (IsdB) confers protection via Th17/IL17 pathway in a murine sepsis model
Amita Joshi et al.
Human Vaccines & Immunotherapeutics (2012)
Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease
Wenjun Ouyang et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 29 (2011)
The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis
Md. Hasan Zaki et al.
CANCER CELL (2011)
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
Eran Elinav et al.
CELL (2011)
Understanding the mechanism of IL-1β secretion
Gloria Lopez-Castejon et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2011)
The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes
Yun-Gi Kim et al.
IMMUNITY (2011)
Suppression of the Inflammatory Immune Response Prevents the Development of Chronic Biofilm Infection Due to Methicillin-Resistant Staphylococcus aureus
Ranjani Prabhakara et al.
INFECTION AND IMMUNITY (2011)
Caspase-1-Processed Cytokines IL-1β and IL-18 Promote IL-17 Production by γδ and CD4 T Cells That Mediate Autoimmunity
Stephen J. Lalor et al.
JOURNAL OF IMMUNOLOGY (2011)
Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut
N. J. Mantis et al.
MUCOSAL IMMUNOLOGY (2011)
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
Eric M. Kofoed et al.
NATURE (2011)
Non-canonical inflammasome activation targets caspase-11
Nobuhiko Kayagaki et al.
NATURE (2011)
Genetics and pathogenesis of inflammatory bowel disease
Bernard Khor et al.
NATURE (2011)
Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
Gregory F. Sonnenberg et al.
NATURE IMMUNOLOGY (2011)
Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
Charles L. Bevins et al.
NATURE REVIEWS MICROBIOLOGY (2011)
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
Sylvain Normand et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine
Shipra Vaishnava et al.
SCIENCE (2011)
Emerging inflammasome effector mechanisms
Mohamed Lamkanfi
NATURE REVIEWS IMMUNOLOGY (2011)
Differential Requirement for Caspase-1 Autoproteolysis in Pathogen-Induced Cell Death and Cytokine Processing
Petr Broz et al.
CELL HOST & MICROBE (2010)
Clostridium difficile Toxin-Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome
Jeffrey Ng et al.
GASTROENTEROLOGY (2010)
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
Christian Bauer et al.
GUT (2010)
The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
Md. Hasan Zaki et al.
IMMUNITY (2010)
Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases
Jeremy Dupaul-Chicoine et al.
IMMUNITY (2010)
Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis
Richard C. Chou et al.
IMMUNITY (2010)
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
Irving C. Allen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
Rosalba Salcedo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Inflammation in the Central Nervous System and Th17 Responses Are Inhibited by IFN-γ-Induced IL-18 Binding Protein
Jason M. Millward et al.
JOURNAL OF IMMUNOLOGY (2010)
Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia
Mohamed Lamkanfi et al.
JOURNAL OF IMMUNOLOGY (2010)
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
Edward A. Miao et al.
NATURE IMMUNOLOGY (2010)
Molecular mechanisms of necroptosis: an ordered cellular explosion
Peter Vandenabeele et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
Bo Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
Edward A. Miao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
Maria T. Abreu
NATURE REVIEWS IMMUNOLOGY (2010)
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
G. Kroemer et al.
CELL DEATH AND DIFFERENTIATION (2009)
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes
L. Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2009)
The S. Typhimurium Effector SopE Induces Caspase-1 Activation in Stromal Cells to Initiate Gut Inflammation
Andreas J. Mueller et al.
CELL HOST & MICROBE (2009)
Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity
Caroline E. Sutton et al.
IMMUNITY (2009)
Interleukin-1 Receptor Signaling Protects Mice from Lethal Intestinal Damage Caused by the Attaching and Effacing Pathogen Citrobacter rodentium
Sarah L. Lebeis et al.
INFECTION AND IMMUNITY (2009)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Franz G. Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2009)
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
Kendle M. Maslowski et al.
NATURE (2009)
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
Veit Hornung et al.
NATURE (2009)
Common variants at five new loci associated with early-onset inflammatory bowel disease
Marcin Imielinski et al.
NATURE GENETICS (2009)
Pyroptosis: host cell death and inflammation
Tessa Bergsbaken et al.
NATURE REVIEWS MICROBIOLOGY (2009)
Mechanisms of regulated unconventional protein secretion
Walter Nickel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation
Shlomo Z. Ben-Sasson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Nod2 is required for the regulation of commensal microbiota in the intestine
Tanja Petnicki-Ocwieja et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Active caspase-1 is a regulator of unconventional protein secretion
Martin Keller et al.
CELL (2008)
Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
Junichi Hitomi et al.
CELL (2008)
Cell death in the host response to infection
K. Labbe et al.
CELL DEATH AND DIFFERENTIATION (2008)
Intestinal deletion of Pofut1 in the mouse inactivates Notch signaling and causes enterocolitis
Sandra Guilmeau et al.
GASTROENTEROLOGY (2008)
Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease
Lauren A. Zenewicz et al.
IMMUNITY (2008)
P2X7 receptor differentially couples to distinct release pathways for IL-1β in mouse macrophage
Pablo Pelegrin et al.
JOURNAL OF IMMUNOLOGY (2008)
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
Tatsuya Saitoh et al.
NATURE (2008)
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Jeffrey C. Barrett et al.
NATURE GENETICS (2008)
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
Yan Zheng et al.
NATURE MEDICINE (2008)
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
Shipra Vaishnava et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Innate immune recognition at the epithelial barrier drives adaptive immunity: APCs take the back seat
Joerg H. Fritz et al.
TRENDS IN IMMUNOLOGY (2008)
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
T. Fernandes-Alnemri et al.
CELL DEATH AND DIFFERENTIATION (2007)
Distribution of neuronal apoptosis inhibitory protein in human tissues
Johannes K. X. Maier et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)
Nonclassical IL-1β secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
Yan Qu et al.
JOURNAL OF IMMUNOLOGY (2007)
Unravelling the pathogenesis of inflammatory bowel disease
R. J. Xavier et al.
NATURE (2007)
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
Benjamin Faustin et al.
MOLECULAR CELL (2007)
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
Susan L. Fink et al.
CELLULAR MICROBIOLOGY (2006)
Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
Nele Festjens et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2006)
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages
Luigi Franchi et al.
NATURE IMMUNOLOGY (2006)
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf
Edward A. Miao et al.
NATURE IMMUNOLOGY (2006)
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
ED Boyden et al.
NATURE GENETICS (2006)
Are innate immune signaling pathways in plants and animals conserved?
FM Ausubel
NATURE IMMUNOLOGY (2005)
Nod2 mutation in Crohn's disease potentiates NF-κB activity and IL-10 processing
S Maeda et al.
SCIENCE (2005)
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
S Rakoff-Nahoum et al.
CELL (2004)
Age and diet act through distinct isoforms of the class II transactivator gene in mouse intestinal epithelium
IR Sanderson et al.
GASTROENTEROLOGY (2004)
Imbalance between interleukin-1 agonists and antagonists: relationship to severity of inflammatory bowel disease
O Ludwiczek et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2004)
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2
SE Girardin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulphate colitis in mice
H Takagi et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2003)
Interleukin-18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin-18 transgenic mice
T Ishikura et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2003)
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
M Chamaillard et al.
NATURE IMMUNOLOGY (2003)
TNF-α and IFN-γ regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells
P Rosenstiel et al.
GASTROENTEROLOGY (2003)
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
SE Girardin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells
MT Abreu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage
PV Sivakumar et al.
GUT (2002)
IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease
A Corbaz et al.
JOURNAL OF IMMUNOLOGY (2002)
Treatment of T cell-dependent experimental colitis in SCID mice by local administration of an adenovirus expressing IL-18 antisense mRNA
S Wirtz et al.
JOURNAL OF IMMUNOLOGY (2002)
IL-1β-converting enzyme (caspase-1) in intestinal inflammation
B Siegmund et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Rapid secretion of interleukin-1β by microvesicle shedding
A MacKenzie et al.
IMMUNITY (2001)
Dextran sodium sulfate-induced colitis in germ-free IQI/Jic mice
S Kitajima et al.
EXPERIMENTAL ANIMALS (2001)
Pro-inflammatory programmed cell death
BT Cookson et al.
TRENDS IN MICROBIOLOGY (2001)
Salmonella induces macrophage death by caspase-1-dependent necrosis
MA Brennan et al.
MOLECULAR MICROBIOLOGY (2000)
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions
SJ Kang et al.
JOURNAL OF CELL BIOLOGY (2000)