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Yemsratch T. Akalu et al.
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Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase
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Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer
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TAM receptors regulate multiple features of microglial physiology
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Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response
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Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis
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Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells
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Overexpression of MERTK Receptor Tyrosine Kinase in Epithelial Cancer Cells Drives Efferocytosis in a Gain-of-Function Capacity
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JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
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Diversification of TAM receptor tyrosine kinase function
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Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure
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SCIENCE (2014)
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities
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ELIFE (2014)
Contribution of defective PS recognition and efferocytosis to chronic inflammation and autoimmunity
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FRONTIERS IN IMMUNOLOGY (2014)
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MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis
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JOURNAL OF CLINICAL INVESTIGATION (2013)
Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells
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The TIM and TAM Families of Phosphatidylserine Receptors Mediate Dengue Virus Entry
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Genetic Dissection of TAM Receptor-Ligand Interaction in Retinal Pigment Epithelial Cell Phagocytosis
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The Soluble Serum Protein Gas6 Bridges Virion Envelope Phosphatidylserine to the TAM Receptor Tyrosine Kinase Axl to Mediate Viral Entry
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MOLECULAR CANCER THERAPEUTICS (2011)
TAM receptors and the clearance of apoptotic cells
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CLEARANCE OF DYING CELLS IN HEALTHY AND DISEASED IMMUNE SYSTEMS (2010)
Sertoli Cell-Initiated Testicular Innate Immune Response through Toll-Like Receptor-3 Activation Is Negatively Regulated by Tyro3, Axl, and Mer Receptors
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ENDOCRINOLOGY (2010)
Calcium-dependent phospholipid scrambling by TMEM16F
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NATURE (2010)
Functions of TAM RTKs in regulating spermatogenesis and male fertility in mice
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REPRODUCTION (2009)
Gas6-mediated signaling is dependent on the engagement of its gamma-carboxyglutamic acid domain with phosphatidylserine
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Vitamin K-dependent proteins, warfarin, and vascular calcification
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CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)
Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cells
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SCIENCE (2008)
Phosphatidylserine recognition by phagocytes: a view to a kill
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TRENDS IN CELL BIOLOGY (2006)
The role of γ-carboxylation in the anti-apoptotic function of gas6
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JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)
Warfarin and the vitamin K-dependent γ-carboxylation system
R Wallin et al.
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Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins
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Phosphatidylserine on HIV envelope is a cofactor for infection of monocytic cells
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JOURNAL OF IMMUNOLOGY (2003)
Gas6 binding to photoreceptor outer segments requires γ-carboxyglutamic acid (Gla) and Ca2+ and is required for OS phagocytosis by RPE cells in vitro
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EXPERIMENTAL EYE RESEARCH (2002)
Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase
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JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family
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SCIENCE (2001)
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