期刊
ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS
卷 17, 期 4, 页码 264-275出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1871530317666170921142055
关键词
Cardiovascular diseases; endothelial dysfunction; RAS; fermented foods; bioactive peptides; oxidative stress; inflammation
Background and Objective: Increasing evidence has demonstrated that dietary products and their active components are independently or jointly responsible for the apparent reduction of the cardiovascular diseases (CVDs) risk. Discussion: Nowadays, there is a growing attention in the use of nutraceuticals as a new approach for the prevention and management of many diseases, as well as for controlling rising of chronic illnesses with minimal side effects. Food-derived peptides, as well as peptide-rich protein hydrolysates, represent new and valuable tools for the prevention of metabolic and cardiovascular diseases, acting as modulators of oxidative stress, inflammation, and overactivity of the renin-angiotensin system (RAS). Conclusion: This review summarizes the recently published data on antioxidant, anti-inflammatory, and vascular protective properties of nutraceuticals, notably on the effects of food-derived bioactive peptides and protein hydrolysates, paying particular attention to those derived from fermented foods.
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