期刊
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
卷 2017, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2017/1215035
关键词
-
Background. Results on body composition in Crohn's disease (CD) and ulcerative colitis (UC) have been heterogeneous and are lacking from Asia. Present study assessed body composition in CD/UC and correlated it with disease severity/duration. Methods. Patients of CD/UC following between Dec 2014 and Dec 2015 who consented for bioimpedance analysis for body fat measurement were included. Lean mass and fat-free mass index (FFMI) were calculated with standard formulae. Visceral fat area (VFA), subcutaneous fat area (SCA), and visceral to subcutaneous fat ratio (VF/SC) were evaluated in CD patients on abdominal CT. Results. Lean mass in CD (n = 44, mean age: 41.2 +/- 15.8 years, 73% males) was significantly lower than UC (n = 53, mean age: 33.2 +/- 11.2 years, 68% males; 44.2 +/- 7.8 versus 48.3 +/- 8.4 Kg, p = 0.01). In both UC/CD, disease severity was associated with nonsignificant decline in BMI (UC: 22.1 +/- 4.9 versus 20.2 +/- 3.2 versus 19.9 +/- 3.2 kg/m(2), p = 0.23; CD: 22.1 +/- 4.2 versus 19.9 +/- 2.3 versus 19.7 +/- 4.2 kg/m(2), p = 0.18) and fat mass (UC: 10.9 +/- 8.9 versus 8.1 +/- 5.9 versus 5.7 +/- 3.6 kg, p = 0.14; CD: 11.2 +/- 7 versus 7.9 +/- 4.4 versus 7.2 +/- 5.9 kg, p = 0.16), and disease duration was associated with significant decline in FFMI (p < 0.05). In CD, disease severity was associated with nonsignificant decline in SCA and increase in VF/SC. Conclusions. CD patients have lower lean mass than UC. Body fat decreases with increasing disease severity and fat-free mass decreases with increasing disease duration in both UC/CD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据