期刊
APL MATERIALS
卷 5, 期 5, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4974514
关键词
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资金
- National 1000 Young Talent Program
- KIT
- Deutsche Forschungsgemeinschaft (DFG) [GRK 2039]
Metal nanoclusters (NCs), a new type of nanomaterial with unique physicochemical properties, show great potential in many biomedical applications. Understanding their behavior in the complex biological environment is critical not only for designing highly efficient NC-based nanomedicines but also for elucidating the biological impact (e. g., toxicity) of these emerging nanomaterials. In this review, we give an overviewof recent progress in exploring interactions of metal NCs with biological systems, including protein adsorption onto NCs, NC interactions with cells, and also the in vivo behavior of NCs. We also discuss the biological responses to the interactions, key parameters defining the interactions, and current challenges in the exploration of NCs in the complex biological environment. (C) 2017 Author(s).
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