相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Enhanced CAR T-cell engineering using non-viral Sleeping Beauty transposition from minicircle vectors
R. Monjezi et al.
LEUKEMIA (2017)
Treatment of Human B-Cell Lymphomas Using Minicircle DNA Vector Expressing Anti-CD3/CD20 in a Mouse Model
Xiaojuan Pang et al.
HUMAN GENE THERAPY (2017)
Towards effective non-viral gene delivery vector
Michaela Šimčíková et al.
Biotechnology & Genetic Engineering Reviews (2016)
Improvement of DNA minicircle production by optimization of the secondary structure of the 5′-UTR of ParA resolvase
Michaela Simcikova et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2016)
Transgene sequences free of CG dinucleotides lead to high level, long-term expression in the lung independent of plasmid backbone design
Reto P. Bazzani et al.
BIOMATERIALS (2016)
Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer
Chuan Jin et al.
EMBO MOLECULAR MEDICINE (2016)
Cardiac gene therapy: are we there yet?
P. N. Matkar et al.
GENE THERAPY (2016)
Construction of minicircle DNA vectors capable of correcting familial hypercholesterolemia phenotype in a LDLR-deficient mouse model
X. Hou et al.
GENE THERAPY (2016)
TALEN gene editing takes aim on HIV
Ronald Benjamin et al.
HUMAN GENETICS (2016)
Development of a nicking endonuclease-assisted method for the purification of minicircles
Claudia P. A. Alves et al.
JOURNAL OF CHROMATOGRAPHY A (2016)
Part II: Functional delivery of a neurotherapeutic gene to neural stem cells using minicircle DNA and nanoparticles: Translational advantages for regenerative neurology
Alinda R. Fernandes et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Minicircle DNA purification using a CIM® DEAE-1 monolithic support
Tatiana Diamantino et al.
JOURNAL OF SEPARATION SCIENCE (2016)
Advanced Design of Dumbbell-shaped Genetic Minimal Vectors Improves Non-coding and Coding RNA Expression
Xiaoou Jiang et al.
MOLECULAR THERAPY (2016)
The Mucus Barrier to Inhaled Gene Therapy
Gregg A. Duncan et al.
MOLECULAR THERAPY (2016)
Non-integrating lentiviral vectors based on the minimal S/MAR sequence retain transgene expression in dividing cells
Zhen Xu et al.
SCIENCE CHINA-LIFE SCIENCES (2016)
A polyvalent influenza DNA vaccine applied by needle-free intradermal delivery induces cross-reactive humoral and cellular immune responses in pigs
Marie Borggren et al.
VACCINE (2016)
Development of rAAV2-CFTR: History of the First rAAV Vector Product to be Used in Humans
Heather S. Loring et al.
HUMAN GENE THERAPY METHODS (2016)
Recent progress in nanomaterials for gene delivery applications
Erhan Keles et al.
BIOMATERIALS SCIENCE (2016)
Production of Double-stranded DNA Ministrings
Shirley Wong et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2016)
Effects of Circular DNA Length on Transfection Efficiency by Electroporation into HeLa Cells
Benjamin D. Hornstein et al.
PLOS ONE (2016)
Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer
Mustafa M. Munye et al.
SCIENTIFIC REPORTS (2016)
Lentiviral-mediated phenotypic correction of cystic fibrosis pigs
Ashley L. Cooney et al.
JCI INSIGHT (2016)
An EBV-Based Plasmid Can Replicate and Maintain in Stem Cells
Seyed Mohammad Ali Hosseini Rad et al.
BIOTECHNOLOGY PROGRESS (2015)
Gas-generating TPGS-PLGA microspheres loaded with nanoparticles (NIMPS) for co-delivery of minicircle DNA and anti-tumoral drugs
Vitor M. Gaspar et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2015)
Influenza Plasmid DNA Vaccines: Progress and Prospects
Diana Bicho et al.
CURRENT GENE THERAPY (2015)
Bioreducible poly(2-ethyl-2-oxazoline)-PLA-PEI-SS triblock copolymer micelles for co-delivery of DNA minicircles and Doxorubicin
Vitor M. Gaspar et al.
JOURNAL OF CONTROLLED RELEASE (2015)
Detecting cancers through tumor-activatable minicircles that lead to a detectable blood biomarker
John A. Ronald et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Induction of pluripotency in human umbilical cord mesenchymal stem cells in feeder layer-free condition
Nasibeh Daneshvar et al.
TISSUE & CELL (2015)
Improvement of the Immunogenicity of Porcine Circovirus Type 2 DNA Vaccine by Recombinant ORF2 Gene and CpG Motifs
Jun Li et al.
VIRAL IMMUNOLOGY (2015)
Generation of human iPSCs from cells of fibroblastic and epithelial origin by means of the oriP/EBNA-1 episomal reprogramming system
Anna M. Drozd et al.
STEM CELL RESEARCH & THERAPY (2015)
Vector optimization and needle-free intradermal application of a broadly protective polyvalent influenza A DNA vaccine for pigs and humans
Marie Borggren et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2015)
Increasing the minicircle DNA purity using an enhanced triplex DNA technology to eliminate DNA contaminants
Xiaohu H. Hou et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2015)
Minicircle DNA vectors for gene therapy: advances and applications
Vitor Gaspar et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2015)
Physical Characterization of Gemini Surfactant-Based Synthetic Vectors for the Delivery of Linear Covalently Closed (LCC) DNA Ministrings
Chi Hong Sum et al.
PLOS ONE (2015)
Combining Random Gene Fission and Rational Gene Fusion To Discover Near-Infrared Fluorescent Protein Fragments That Report on Protein-Protein Interactions
Naresh Pandey et al.
ACS SYNTHETIC BIOLOGY (2015)
Mechanisms of Theta Plasmid Replication
Joshua Lilly et al.
MICROBIOLOGY SPECTRUM (2015)
Functions of Noncoding Sequences in Mammalian Genomes
L. I. Patrushev et al.
BIOCHEMISTRY-MOSCOW (2014)
Improving DNA Vaccine Performance Through Vector Design
James A. Williams
CURRENT GENE THERAPY (2014)
Adenovirus Vectors for Gene Therapy, Vaccination and Cancer Gene Therapy
William Wold et al.
CURRENT GENE THERAPY (2014)
Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung
E. W. F. W. Alton et al.
GENE THERAPY (2014)
Short Hairpin RNA Gene Silencing of Prolyl Hydroxylase-2 with a Minicircle Vector Improves Neovascularization of Hindlimb Ischemia
Maarten A. Lijkwan et al.
HUMAN GENE THERAPY (2014)
Poly(2-ethyl-2-oxazoline)-PLA-g-PEI amphiphilic triblock micelles for co-delivery of minicircle DNA and chemotherapeutics
Vitor M. Gaspar et al.
JOURNAL OF CONTROLLED RELEASE (2014)
In Vivo Electroporation of Minicircle DNA as a Novel Method of Vaccine Delivery To Enhance HIV-1-Specific Immune Responses
Qingtao Wang et al.
JOURNAL OF VIROLOGY (2014)
Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector
Dennis Kobelt et al.
MOLECULAR ONCOLOGY (2014)
Non-viral vectors for gene-based therapy
Hao Yin et al.
NATURE REVIEWS GENETICS (2014)
S/MAR sequence confers long-term mitotic stability on non-integrating lentiviral vector episomes without selection
Santhosh Chakkaramakkil Verghese et al.
NUCLEIC ACIDS RESEARCH (2014)
Clinical evaluation of CpG oligonucleotides as adjuvants for vaccines targeting infectious diseases and cancer
Julia Scheiermann et al.
VACCINE (2014)
A New Strategy to Deliver Synthetic Protein Drugs: Self-reproducible Biologics Using Minicircles
Hyoju Yi et al.
SCIENTIFIC REPORTS (2014)
Self in vivo production of a synthetic biological drug CTLA4Ig using a minicircle vector
Yeri Alice Rim et al.
SCIENTIFIC REPORTS (2014)
Improved Minicircle DNA Biosynthesis for Gene Therapy Applications
Vitor M. Gaspar et al.
HUMAN GENE THERAPY METHODS (2014)
Safety and efficacy of DNA vaccines Plasmids vs. minicircles
Sofia Stenler et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2014)
Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression
Sofia Stenler et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2014)
DNA Ministrings: Highly Safe and Effective Gene Delivery Vectors
Nafiseh Nafissi et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2014)
Lung gene therapy-How to capture illumination from the light already present in the tunnel
Emily Xia et al.
GENES & DISEASES (2014)
Development of Antibiotic-Free Selection System for Safer DNA Vaccination
Jeremy M. Luke et al.
DNA VACCINES: METHODS AND PROTOCOLS, 3RD EDITION (2014)
Episomal Maintenance of S/MAR-Containing Non-Viral Vectors for RPE-Based Diseases
Adarsha Koirala et al.
RETINAL DEGENERATIVE DISEASES: MECHANISMS AND EXPERIMENTAL THERAPY (2014)
A Genetically Encoded AND Gate for Cell-Targeted Metabolic Labeling of Proteins
Alborz Mahdavi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
A Mini-intronic Plasmid (MIP): A Novel Robust Transgene Expression Vector In Vivo and In Vitro
Jiamiao Lu et al.
MOLECULAR THERAPY (2013)
Minicircle DNA is Superior to Plasmid DNA in Eliciting Antigen-specific CD8+ T-cell Responses
Wynette M. Dietz et al.
MOLECULAR THERAPY (2013)
Marker-free plasmids for biotechnological applications - implications and perspectives
Pedro H. Oliveira et al.
TRENDS IN BIOTECHNOLOGY (2013)
Supercoiled Minivector DNA resists shear forces associated with gene therapy delivery
D. J. Catanese et al.
GENE THERAPY (2012)
The Extragenic Spacer Length Between the 5′ and 3′ Ends of the Transgene Expression Cassette Affects Transgene Silencing From Plasmid-based Vectors
Jiamiao Lu et al.
MOLECULAR THERAPY (2012)
Construction and Characterization of an in-vivo Linear Covalently Closed DNA Vector Production System
Nafiseh Nafissi et al.
MICROBIAL CELL FACTORIES (2012)
Pre-Clinical Development of BCG.HIVACAT, an Antibiotic-Free Selection Strain, for HIV-TB Pediatric Vaccine Vectored by Lysine Auxotroph of BCG
Narcis Saubi et al.
PLOS ONE (2012)
A Novel Micro-Linear Vector for In Vitro and In Vivo Gene Delivery and Its Application for EBV Positive Tumors
Hong-Sheng Wang et al.
PLOS ONE (2012)
Gene therapy in the Cornea: 2005-present
Rajiv R. Mohan et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2012)
Intratumoral Dispersion, Retention, Systemic Biodistribution, and Clearance of a Small-Size Tumor Necrosis Factor-α-Expressing MIDGE Vector After Nonviral in Vivo Jet-Injection Gene Transfer
Nele Galling et al.
HUMAN GENE THERAPY METHODS (2012)
Biomedical application of plasmid DNA in gene therapy: A new challenge for chromatography
F. Sousa et al.
Biotechnology & Genetic Engineering Reviews (2011)
Plasmid-mediated gene therapy for cardiovascular disease
Paul D. Williams et al.
CARDIOVASCULAR RESEARCH (2011)
Double Knockdown of Prolyl Hydroxylase and Factor-Inhibiting Hypoxia-Inducible Factor With Nonviral Minicircle Gene Therapy Enhances Stem Cell Mobilization and Angiogenesis After Myocardial Infarction
Mei Huang et al.
CIRCULATION (2011)
New Japanese encephalitis vaccines: alternatives to production in mouse brain
Scott B. Halstead et al.
EXPERT REVIEW OF VACCINES (2011)
CpG DNA as a vaccine adjuvant
Christian Bode et al.
EXPERT REVIEW OF VACCINES (2011)
Transfection of shRNA-encoding Minivector DNA of a few hundred base pairs to regulate gene expression in lymphoma cells
N. Zhao et al.
GENE THERAPY (2011)
Halting angiogenesis by non-viral somatic gene therapy alleviates psoriasis and murine psoriasiform skin lesions
John R. Zibert et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver
Orestis Argyros et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2011)
New Generation of Plasmid Backbones Devoid of Antibiotic Resistance Marker for Gene Therapy Trials
Gaelle Vandermeulen et al.
MOLECULAR THERAPY (2011)
Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
Michael S. D. Kormann et al.
NATURE BIOTECHNOLOGY (2011)
Nuclear Scaffold Attachment Sites within ENCODE Regions Associate with Actively Transcribed Genes
Mignon A. Keaton et al.
PLOS ONE (2011)
The introduction of multi-copy CpG motifs into an antiviral DNA vaccine strongly up-regulates its immunogenicity in fish
S. Martinez-Alonso et al.
VACCINE (2011)
Plasmid containing CpG motifs enhances the efficacy of porcine reproductive and respiratory syndrome live attenuated vaccine
Xiaoyu Guo et al.
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2011)
MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease
Shijun Hu et al.
CIRCULATION (2010)
Marker-free plasmids for gene therapeutic applications-Lack of antibiotic resistance gene substantially improves the manufacturing process
Juergen Mairhofer et al.
JOURNAL OF BIOTECHNOLOGY (2010)
pFARs, Plasmids free of antibiotic resistance markers, display high-level transgene expression in muscle, skin and tumour cells
Corinne Marie et al.
JOURNAL OF GENE MEDICINE (2010)
A nonviral minicircle vector for deriving human iPS cells
Fangjun Jia et al.
NATURE METHODS (2010)
Tightly-wound miniknot vectors for gene therapy: A potential improvement over supercoiled minicircle DNA
Oleg E. Tolmachov
MEDICAL HYPOTHESES (2010)
Antibiotic-free selection in E. coli: new considerations for optimal design and improved production
Isabelle Peubez et al.
MICROBIAL CELL FACTORIES (2010)
Immune response induced by a linear DNA vector: Influence of dose, formulation and route of injection
Anne Endmann et al.
VACCINE (2010)
Oral delivery of a DNA vaccine against tuberculosis using operator-repressor titration in a Salmonella enterica vector
Jen-Min Huang et al.
VACCINE (2010)
Biosafety of DNA vaccines: New generation of DNA vectors and current knowledge on the fate of plasmids after injection
Florence Faurez et al.
VACCINE (2010)
Nonviral Gene Delivery: Principle, Limitations, and Recent Progress
Mohammed S. Al-Dosari et al.
AAPS JOURNAL (2009)
Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
Joerg Vollmer et al.
ADVANCED DRUG DELIVERY REVIEWS (2009)
Progress and Prospects: prospects of repeated pulmonary administration of viral vectors
P. L. Sinn et al.
GENE THERAPY (2009)
Avidin Fusion Protein-Expressing Lentiviral Vector for Targeted Drug Delivery
Hanna P. Lesch et al.
HUMAN GENE THERAPY (2009)
Gene Transfer to Mouse Heart and Skeletal Muscles Using a Minicircle Expressing Human Vascular Endothelial Growth Factor
Sofia Stenler et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2009)
Efficient stable gene transfer into human cells by the Sleeping Beauty transposon vectors
Zsuzsanna Izsvak et al.
METHODS (2009)
Enhanced vaccine antigen delivery by Salmonella using antibiotic-free operator-repressor titration-based plasmid stabilisation compared to chromosomal integration
Matthew W. Leckenby et al.
MICROBIAL PATHOGENESIS (2009)
Sonoporation of the Minicircle-VEGF(165) for Wound Healing of Diabetic Mice
C. S. Yoon et al.
PHARMACEUTICAL RESEARCH (2009)
Antibiotic resistance free plasmid DNA expressing LACK protein leads towards a protective Th1 response against Leishmania infantum infection
I. Ramos et al.
VACCINE (2009)
Improved antibiotic-free DNA vaccine vectors utilizing a novel RNA based plasmid selection system
Jeremy Luke et al.
VACCINE (2009)
CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses
Ralf Geiben-Lynn et al.
BLOOD (2008)
Plasmid selection in Escherichia coli using an endogenous essential gene marker
Shan Goh et al.
BMC BIOTECHNOLOGY (2008)
Rational vector design for efficient non-viral gene delivery: Challenges facing the use of plasmid DNA
Juergen Mairhofer et al.
MOLECULAR BIOTECHNOLOGY (2008)
Gene Therapy for Diabetes: Metabolic Effects of Helper-dependent Adenoviral Exendin 4 Expression in a Diet-induced Obesity Mouse Model
Susan L. Samson et al.
MOLECULAR THERAPY (2008)
Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation
Zhi-Ying Chen et al.
MOLECULAR THERAPY (2008)
Modification of adenovirus gene transfer vectors with synthetic polymers: A scientific review and technical guide
Florian Kreppel et al.
MOLECULAR THERAPY (2008)
Therapeutic angiogenesis with intramuscular NV1FGF improves amputation-free survival in patients with critical limb ischemia
Sigrid Nikol et al.
MOLECULAR THERAPY (2008)
Anti-tumor effect of DNA-based vaccination and dSLIM immunomodulatory molecules in mice with Ph+ acute lymphoblastic leukaemia
Joachim Koechling et al.
VACCINE (2008)
Universal strategies in research and drug discovery based on protein-fragment complementation assays
Stephen W. Michnick et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
An array of Escherichia coli clones over-expressing essential proteins:: A new strategy of identifying cellular targets of potent antibacterial compounds
H. Howard Xu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Designing nonviral vectors for efficient gene transfer and long-term gene expression
Dean A. Jackson et al.
MOLECULAR THERAPY (2006)
Influence of plasmid DNA topology on the transfection properties of DOTAP/DOPE lipoplexes
Katrien Remaut et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Minicircle-IFNγ induces antiproliferative and antitumoral effects in human nasopharyngeal carcinoma
Jiangxue Wu et al.
CLINICAL CANCER RESEARCH (2006)
Nuclear-targeted minicircle to enhance gene transfer with non-viral vectors in vitro and in vivo
Laurence Vaysse et al.
JOURNAL OF GENE MEDICINE (2006)
Exploring writhe in supercoiled minicircle DNA
Jonathan M. Fogg et al.
JOURNAL OF PHYSICS-CONDENSED MATTER (2006)
Intramuscular gene transfer of fibroblast growth factor-1 using improved pCOR plasmid design stimulates collateral formation in a rabbit ischemic hindlimb model
B Witzenbichler et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
Production of fuculose-1-phosphate aldolase using operator-repressor titration for plasmid maintenance in high cell density Escherichia coli fermentations
O Durany et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
Separate-component-stabilization system for protein and DNA production without the use of antibiotics
CY Szpirer et al.
BIOTECHNIQUES (2005)
Antibiotic-free plasmid stabilization by operator-repressor titration for vaccine delivery by using live Salmonella entetica serovar Typhimurium
HS Garmory et al.
INFECTION AND IMMUNITY (2005)
Improvement of pCOR plasmid copy number for pharmaceutical applications
F Soubrier et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2005)
DNA immunisation with minimalistic expression constructs
S Moreno et al.
VACCINE (2004)
A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans
M Mwau et al.
JOURNAL OF GENERAL VIROLOGY (2004)
Gene therapy for cystic fibrosis: an example for lung gene therapy
U Griesenbach et al.
GENE THERAPY (2004)
Nonviral DNA vectors for immunization and therapy:: design and methods for their obtention
EG Rodríguez
JOURNAL OF MOLECULAR MEDICINE-JMM (2004)
Effect of plasmid copy number and lac operator sequence on antibiotic-free plasmid selection by operator-repressor titration in Escherichia coli
RM Cranenburgh et al.
JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY (2004)
Emerging significance of plasmid DNA nuclear import in gene therapy
FM Munkonge et al.
ADVANCED DRUG DELIVERY REVIEWS (2003)
Progress and problems with the use of viral vectors for gene therapy
CE Thomas et al.
NATURE REVIEWS GENETICS (2003)
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
S Hacein-Bey-Abina et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Current status of gene therapy for inherited lung diseases
RA Driskell et al.
ANNUAL REVIEW OF PHYSIOLOGY (2003)
DNA vaccination with linear minimalistic (MIDGE) vectors confers protection against Leishmania major infection in mice
L López-Fuertes et al.
VACCINE (2002)
An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy
BW Bigger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Priming of immune responses to hepatitis B surface antigen with minimal DNA expression constructs modified with a nuclear localization signal peptide
R Schirmbeck et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2001)
A novel minimal-size vector (MIDGE) improves transgene expression in colon carcinoma cells and avoids transfection of undesired DNA
F Schakowski et al.
MOLECULAR THERAPY (2001)
Escherichia coli strains that allow antibiotic-free plasmid selection and maintenance by repressor titration
Rocky M. Cranenburgh et al.
NUCLEIC ACIDS RESEARCH (2001)
Therapeutic vaccination against metastatic carcinoma by expression-modulated and immunomodified autologous tumor cells:: A first clinical phase I/II trial
B Wittig et al.
HUMAN GENE THERAPY (2001)
Catheter-based plasmid-mediated transfer of genes into ischemic myocardium using the pCOR plasmid
R Kornowski et al.
CORONARY ARTERY DISEASE (2000)
Episomal vectors for gene expression in mammalian cells
K Van Craenenbroeck et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
分享论文
