期刊
FRONTIERS IN PHARMACOLOGY
卷 8, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fphar.2017.00664
关键词
hydrogen sulfide; donor; cancer; glucose metabolism
资金
- National Institutes of Health of United States [R01HL116571]
- Natural Science Foundation of Guangdong Province in China [2017A030313892]
- Science and Technology Planning Project of Guangzhou city in China [201510010201]
- Projects of Colleges and Universities directly under the Guangzhou Education Bureau [1201620148]
- National Funds for developing local colleges and universities [B16056001]
- Teaching Reform Projects of Higher Education in Guangdong Colleges and Universities [2016430]
As an important endogenous gaseous signaling molecule, hydrogen sulfide (H2S) exerts various effects in the body. A variety of pathological changes, such as cancer, glycometabolic disorders, and diabetes, are associated with altered endogenous levels of H2S, especially decreased. Therefore, the supplement of H2S is of great significance for the treatment of diseases containing the above pathological changes. At present, many efforts have been made to increase the in vivo levels of H2S by administration of gaseous H2S, simple inorganic sulfide salts, sophisticated synthetic slow-releasing controllable H2S donors or materials, and using H2S stimulating agents. In this article, we reviewed the recent development of H2S releasing/stimulating reagents and their potential applications in two common pathological processes including cancer and glycometabolic disorders.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据