相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Neuronal and molecular effects of cannabidiol on the mesolimbic dopamine system: Implications for novel schizophrenia treatments
Justine Renard et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2017)
Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia
Marco Aurelio Mori et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2017)
In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease
Georgia Watt et al.
FRONTIERS IN PHARMACOLOGY (2017)
Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn's Disease, a Randomized Controlled Trial
Timna Naftali et al.
DIGESTIVE DISEASES AND SCIENCES (2017)
HU-446 and HU-465, Derivatives of the Non-psychoactive Cannabinoid Cannabidiol, Decrease the Activation of Encephalitogenic T Cells
Ewa Kozela et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2016)
Synthesis of (-)-Cannabimovone and Structural Reassignment of Anhydrocannabimovone through Gold(I)-Catalyzed Cycloisomerization
Javier Carreras et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice
Aine M. McKillop et al.
DIABETOLOGIA (2016)
THC:CBD in Daily Practice: Available Data from UK, Germany and Spain
Oscar Fernandez
EUROPEAN NEUROLOGY (2016)
Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment
Regina M. Krohn et al.
JOURNAL OF INFLAMMATION-LONDON (2016)
Evolution of the Cannabinoid and Terpene Content during the Growth of Cannabis sativa Plants from Different Chemotypes
Oier Aizpurua-Olaizola et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Atropisomerism about Aryl-C(sp3) Bonds: Conformational Behavior of Substituted Phenylcyclohexanes in Solution
Manon Flos et al.
JOURNAL OF ORGANIC CHEMISTRY (2016)
Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial
Orrin Devinsky et al.
LANCET NEUROLOGY (2016)
Phytocannabinoids: a unified critical inventory
Lumir Ondrej Hanus et al.
NATURAL PRODUCT REPORTS (2016)
Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects
Aviva Breuer et al.
PLOS ONE (2016)
Discovery of KLS-13019, a Cannabidiol-Derived Neuroprotective Agent, with Improved Potency, Safety, and Permeability
William A. Kinney et al.
ACS MEDICINAL CHEMISTRY LETTERS (2016)
Allosteric Modulators of the CB1 Cannabinoid Receptor: A Structural Update Review
Paula Morales et al.
CANNABIS AND CANNABINOID RESEARCH (2016)
Human Metabolites of Cannabidiol: A Review on Their Formation, Biological Activity, and Relevance in Therapy
Istvan Ujvary et al.
CANNABIS AND CANNABINOID RESEARCH (2016)
Cannabidiol (CBD) and its analogs: a review of their effects on inflammation
Sumner Burstein
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor
R. B. Laprairie et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Progress report on new antiepileptic drugs: A summary of the Twelfth Eilat Conference (EILAT XII)
Meir Bialer et al.
EPILEPSY RESEARCH (2015)
Fatty Acid-binding Proteins (FABPs) Are Intracellular Carriers for Δ9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD)
Matthew W. Elmes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Cannabidiol-2′,6′-dimethyl ether stimulates body weight gain in apolipoprotein E-deficient BALB/c. KOR/Stm Slc-Apoeshl mice
Shuso Takeda et al.
JOURNAL OF TOXICOLOGICAL SCIENCES (2015)
Evaluation of Serum Cytokines Levels and the Role of Cannabidiol Treatment in Animal Model of Asthma
Francieli Vuolo et al.
MEDIATORS OF INFLAMMATION (2015)
Molecular Targets of Cannabidiol in Neurological Disorders
Clementino Ibeas Bih et al.
NEUROTHERAPEUTICS (2015)
CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency
Reem Smoum et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Cannabidiol improves lung function and inflammation in mice submitted to LPS-induced acute lung injury
A. Ribeiro et al.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2015)
The Effect of Cannabidiol on Ischemia/Reperfusion-Induced Ventricular Arrhythmias: The Role of Adenosine A1 Receptors
Ersoz Gonca et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2015)
HU-444, a Novel, Potent Anti-Inflammatory, Nonpsychotropic Cannabinoid
Christeene G. Haj et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Activation of GPR18 by cannabinoid compounds: a tale of biased agonism
Linda Console-Bram et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
HU-331 Is a Catalytic Inhibitor of Topoisomerase Ilα
Kellie M. Regal et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2014)
Antidepressant-Like and Anxiolytic-Like Effects of Cannabidiol: A Chemical Compound of Cannabis sativa
Alexandre R. de Mello Schier et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2014)
Atropisomerism about Aryl-Csp3 Bonds: The Electronic and Steric Influence of ortho-Substituents on Conformational Exchange in Cannabidiol and Linderatin Derivatives
Hatice Berber et al.
JOURNAL OF ORGANIC CHEMISTRY (2014)
Early phytocannabinoid chemistry to endocannabinoids and beyond
Raphael Mechoulam et al.
NATURE REVIEWS NEUROSCIENCE (2014)
Differences in receptor binding affinity of several phytocannabinoids do not explain their effects on neural cell cultures
Sarah Rosenthaler et al.
NEUROTOXICOLOGY AND TERATOLOGY (2014)
Cannabidiol Promotes Amyloid Precursor Protein Ubiquitination and Reduction of Beta Amyloid Expression in SHSY5YAPP+ Cells Through PPARγ Involvement
Caterina Scuderi et al.
PHYTOTHERAPY RESEARCH (2014)
Δ9-THC and N-arachidonoyl glycine regulate BV-2 microglial morphology and cytokine release plasticity: rnplications for signaling at GPR18
Douglas McHugh et al.
FRONTIERS IN PHARMACOLOGY (2014)
Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease
Francesca Borrelli et al.
BIOCHEMICAL PHARMACOLOGY (2013)
Structural Requirements for Potent Direct Inhibition of Human Cytochrome P450 1A1 by Cannabidiol: Role of Pentylresorcinol Moiety
Satoshi Yamaori et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2013)
Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
Javier Fernandez-Ruiz et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Cannabidiol as potential anticancer drug
Paola Massi et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism
T. D. M. Hill et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Epigenetic control of skin differentiation genes by phytocannabinoids
Mariangela Pucci et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation
Carmen Petronzi et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2013)
Therapeutic Utility of Cannabinoid Receptor Type 2 (CB2) Selective Agonists
Sangdon Han et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Anti-Inflammatory Role of Cannabidiol and O-1602 in Cerulein-Induced Acute Pancreatitis in Mice
Kun Li et al.
PANCREAS (2013)
Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation
L. De Petrocellis et al.
ACTA PHYSIOLOGICA (2012)
Cannabidivarin is anticonvulsant in mouse and rat
A. J. Hill et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus
E. M. Rock et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Δ9-Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells
Douglas McHugh et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Curcumin nanoformulations: a future nanomedicine for cancer
Murali M. Yallapu et al.
DRUG DISCOVERY TODAY (2012)
Modulation of L-α-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids
Sharon Anavi-Goffer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
Wei Xiong et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration
Shuso Takeda et al.
TOXICOLOGY LETTERS (2012)
Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
F. M. Leweke et al.
TRANSLATIONAL PSYCHIATRY (2012)
Cannabidiol in Humans-The Quest for Therapeutic Targets
Simon Zhornitsky et al.
PHARMACEUTICALS (2012)
Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa
Lucia Renee Ruhaak et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)
Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis
Sean D. McAllister et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action
Sabatino Maione et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans
Silvana Y. Romero-Zerbo et al.
JOURNAL OF ENDOCRINOLOGY (2011)
Ferruginenes A-C from Rhododendron ferrugineum and Their Cytotoxic Evaluation
Prapairat Seephonkai et al.
JOURNAL OF NATURAL PRODUCTS (2011)
Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study
Lourdes Ruiz-Valdepenas et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Cannabidiol Reduces Ab- Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement
Giuseppe Esposito et al.
PLOS ONE (2011)
Cannabidiol Reduces Brain Damage and Improves Functional Recovery After Acute Hypoxia-Ischemia in Newborn Pigs
Hector Lafuente et al.
PEDIATRIC RESEARCH (2011)
Evidence that the plant cannabinoid cannabigerol is a highly potent alpha(2)-adrenoceptor agonist and moderately potent 5HT(1A) receptor antagonist
M. G. Cascio et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Phytocannabinoids beyond the Cannabis plant - do they exist?
Juerg Gertsch et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
A role for L-α-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells
Lesley A. Ford et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Cannabimovone, a Cannabinoid with a Rearranged Terpenoid Skeleton from Hemp
Orazio Taglialatela-Scafati et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2010)
The Nonpsychoactive Cannabinoid Cannabidiol Inhibits 5-Hydroxytryptamine3A Receptor-Mediated Currents in Xenopus laevis Oocytes
Keun-Hang Yang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology
Sagnik Bhattacharyya et al.
NEUROPSYCHOPHARMACOLOGY (2010)
The Challenge of Atropisomerism in Drug Discovery
Jonathan Clayden et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Cannabidiol-2′,6′-Dimethyl Ether, a Cannabidiol Derivative, Is a Highly Potent and Selective 15-Lipoxygenase Inhibitor
Shuso Takeda et al.
DRUG METABOLISM AND DISPOSITION (2009)
Time-dependent vascular actions of cannabidiol in the rat aorta
Saoirse E. O'Sullivan et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Lipid G Protein-coupled Receptor Ligand Identification Using β-Arrestin PathHunter™ Assay
Hong Yin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Nonpsychotropic Cannabinoid Cannabidiol Modulates and Directly Activates Alpha-1 and Alpha-1-Beta Glycine Receptor Function
Joerg Ahrens et al.
PHARMACOLOGY (2009)
The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo
Lauren S. Whyte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis
Shuso Takeda et al.
DRUG METABOLISM AND DISPOSITION (2008)
Antibacterial cannabinoids from Cannabis sativa:: A structure-activity study
Giovanni Appendino et al.
JOURNAL OF NATURAL PRODUCTS (2008)
GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current
Jane E. Lauckner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects
D. G. Johns et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
The orphan receptor GPR55 is a novel cannabinoid receptor
E. Ryberg et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Meta-analysis of cannabinoid ligand binding affinity and receptor distribution: interspecies differences
J. M. McPartland et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro
A. Thomas et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Pivotal Advance:: Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis
Mohanraj Rajesh et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Identification of GPR55 as a lysophosphatidylinositol receptor
Saori Oka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
CB2-receptor stimulation attenuates TNF-α-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion
Mohanraj Rajesh et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
A general route to 5,6-seco-hexahydrodibenzopyrans and analogues:: first total synthesis of (+)-Machaeridiol B and (+)-Machaeriol B
Qinggang Huang et al.
TETRAHEDRON (2007)
HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor
Natalya M. Kogan et al.
MOLECULAR CANCER THERAPEUTICS (2007)
HU-331: a cannabinoid quinone, with uncommon cytotoxic properties and low toxicity
Maximilian Peters et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2007)
Cannabidiol - Recent advances
Raphael Mechoulam et al.
CHEMISTRY & BIODIVERSITY (2007)
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
Alessia Ligresti et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
New cannabidiol derivatives: Synthesis, binding to cannabinoid receptor, and evaluation of their antiinflammatory activity
S Ben-Shabat et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Chemical constituents of marijuana: The complex mixture of natural cannabinoids
MA ElSohly et al.
LIFE SCIENCES (2005)
Agonistic properties of cannabidiol at 5-HT1a receptors
EB Russo et al.
NEUROCHEMICAL RESEARCH (2005)
Evidence that (-)-7-hydroxy-4′-dimethylheptyl-cannabidiol activates a non-CB1, non-CB2, non-TRPV1 target in the mouse vas deferens
RG Pertwee et al.
NEUROPHARMACOLOGY (2005)
Peripheral, but not central effects of cannabidiol derivatives:: Mediation by CB1 and unidentified receptors
E Fride et al.
NEUROPHARMACOLOGY (2005)
Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptors
LO Hanus et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2005)
A novel synthetic, noripsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis
PF Sumariwalla et al.
ARTHRITIS AND RHEUMATISM (2004)
(+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only
E Fride et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Synthesis and antitumor activity of quinonoid derivatives of cannabinoids
NM Kogan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Antimicrobial and antiparasitic (+)-trans-hexahydrodibenzopyrans and analogues from Machaerium multiflorum
I Muhammad et al.
JOURNAL OF NATURAL PRODUCTS (2003)
Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects
R Mechoulam et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2002)
(-)-cannabidiol antagonizes cannabinoid receptor agonists and noradrenaline in the mouse vas deferens
RG Pertwee et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
T Bisogno et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Synthesis of a primary metabolite of cannabidiol
S Tchilibon et al.
ORGANIC LETTERS (2000)
分享论文
